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Assessment of frailty in patients with heart failure: A new Heart Failure Frailty Score developed by Delphi consensus.

Vitale, C; Berthelot, E; Coats, AJS; Loreena, H; Albert, NM; Tkaczyszyn, M; Adamopoulos, S; Anderson, L; Anker, MS; Anker, SD; et al. Vitale, C; Berthelot, E; Coats, AJS; Loreena, H; Albert, NM; Tkaczyszyn, M; Adamopoulos, S; Anderson, L; Anker, MS; Anker, SD; Bell, D; Ben-Gal, T; Bistola, V; Bozkurt, B; Brooks, P; Camafort, M; Carrero, JJ; Chioncel, O; Choi, D-J; Chung, W-J; Doehner, W; Fernández-Bergés, D; Ferrari, R; Fiuzat, M; Gomez-Mesa, JE; Gustafsson, F; Jankowska, E; Kang, S-M; Kinugawa, K; Khunti, K; Hobbs, FDR; Lee, C; Lopatin, Y; Maddocks, M; Maltese, G; Marques-Sule, E; Matsue, Y; Miró, Ò; Moura, B; Piepoli, M; Ponikowski, P; Pulignano, G; Rakisheva, A; Ray, R; Sciacqua, A; Seferovic, P; Sentandreu-Mañó, T; Sze, S; Sinclair, A; Strömberg, A; Theou, O; Tsutsui, H; Uchmanowicz, I; Vidan, MT; Volterrani, M; von Haehling, S; Yoo, B; Zhang, J; Zhang, Y; Metra, M; Rosano, GMC (2025) Assessment of frailty in patients with heart failure: A new Heart Failure Frailty Score developed by Delphi consensus. ESC Heart Fail, 12 (3). pp. 1818-1831. ISSN 2055-5822 https://doi.org/10.1002/ehf2.15187
SGUL Authors: Anderson, Lisa Ray, Robin

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Abstract

AIMS: The Heart Failure Frailty Score (HFFS) is a novel, multidimensional tool to assess frailty in patients with heart failure (HF). It has been developed to overcome limitations of existing frailty assessment tools while being practical for clinical use. The HFFS reflects the concept of frailty as a multidimensional, dynamic and potentially reversible state, which increases vulnerability to stressors and risk of poor outcomes in patients with HF. METHODS AND RESULTS: The HFFS was developed through a Delphi consensus process involving 54 international experts. This approach involved iterative rounds of questionnaires and interviews, where a panel of experts provided their opinions on specific questions prepared by the Steering Committee. The experts were invited to vote and share their views anonymously, using a 5-point Likert scale over iterative rounds. An 80% threshold was set for agreement or disagreement for each statement. Twenty-two variables from four domains (clinical, functional, psycho-cognitive and social) have been selected for inclusion in the HFFS after the third round of the Delphi process. A shorter version (S-HFFS), including 10 variables, has also been developed for daily clinical use. CONCLUSIONS: The HFFS is a new multidimensional tool for the identification of frailty in patients with HF. It should also enables healthcare providers to identify potential 'red flags' for frailty in order to develop personalized care plans. The next step will be to validate the new score in patients with HF.

Item Type: Article
Additional Information: © 2025 The Author(s). ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Keywords: Frailty, Heart failure, Management, Prognosis, Score, Heart failure, Frailty, Management, Prognosis, Score, 1102 Cardiorespiratory Medicine and Haematology
SGUL Research Institute / Research Centre: Academic Structure > Cardiovascular & Genomics Research Institute
Academic Structure > Cardiovascular & Genomics Research Institute > Clinical Cardiology
Journal or Publication Title: ESC Heart Fail
ISSN: 2055-5822
Language: eng
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
PubMed ID: 39904922
Web of Science ID: WOS:001412579900001
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/117216
Publisher's version: https://doi.org/10.1002/ehf2.15187

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