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Practical routes to preregistration: a guide to enhanced transparency and rigour in neuropsychological research

Binney, RJ; Smith, LJ; Rossit, S; Demeyere, N; Learmonth, G; Olgiati, E; Halai, AD; Rounis, E; Evans, J; Edelstyn, NMJ; et al. Binney, RJ; Smith, LJ; Rossit, S; Demeyere, N; Learmonth, G; Olgiati, E; Halai, AD; Rounis, E; Evans, J; Edelstyn, NMJ; McIntosh, RD (2025) Practical routes to preregistration: a guide to enhanced transparency and rigour in neuropsychological research. Brain Communications, 7 (3). fcaf162. ISSN 2632-1297 https://doi.org/10.1093/braincomms/fcaf162
SGUL Authors: Olgiati, Elena

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Abstract

Preregistration is the act of formally documenting a research plan before collecting (or at least before analysing) the data. It allows those reading a final research report to know which aspects of a study were decided before sight of the data, and which were added later. This enables informed evaluation of the severity with which scientific claims have been tested. We, as the British Neuropsychological Society Open Research Group, conducted a survey to explore awareness and adoption of open research practices within our field. Neuropsychology involves the study of relatively rare or hard-to-access participants, creating practical challenges that, according to our survey, are perceived as barriers to preregistration. We survey the available routes to preregistration, and suggest that the barriers are all surmountable in one way or another. However, there is a tension, in that higher levels of bias control require greater restriction over the flexibility of preregistered studies, but such flexibility is often essential for neuropsychological research. Researchers must therefore consider which route provides the right balance of rigour and pragmatic flexibility to render a preregistered project viable for them. By mapping out the issues and potential solutions, and by signposting relevant resources and publication routes, we hope to facilitate well-reasoned decision-making and empower neuropsychologists to enhance the transparency and rigour of their research. Although we focus neuropsychology, our guidance is applicable to any field that studies hard-to-access human samples, or involves arduous or expensive means of data collection.

Item Type: Article
Additional Information: © The Author(s) 2025. Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: best practice, clinical science, open research, publication bias, reproducibility
SGUL Research Institute / Research Centre: Academic Structure > Neuroscience & Cell Biology Research Institute
Academic Structure > Neuroscience & Cell Biology Research Institute > Neuromodulation & Motor Control
Journal or Publication Title: Brain Communications
ISSN: 2632-1297
Language: en
Media of Output: Electronic-eCollection
Related URLs:
Publisher License: Creative Commons: Attribution 4.0
Dates:
Date Event
2025-04-30 Published
2025-04-28 Published Online
2025-04-24 Accepted
URI: https://openaccess.sgul.ac.uk/id/eprint/118225
Publisher's version: https://doi.org/10.1093/braincomms/fcaf162

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