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Consensus on the management of traumatic brain injury in older adults: Results from a Delphi study

Lagares, A; Depreitere, B; Marklund, N; Castano Leon, AM; Posti, JP; Younsi, A; Klein, S; Papadopoulos, M; Stocchetti, N; Robba, C; et al. Lagares, A; Depreitere, B; Marklund, N; Castano Leon, AM; Posti, JP; Younsi, A; Klein, S; Papadopoulos, M; Stocchetti, N; Robba, C; Steiner, LA; Gomez, PA; Aries, M; Bouzat, P; Holling, M; Llompart-Pou, JA; Wolf, S; Belli, A; Czorlich, P; Gierthmuehlen, M; van Essen, TA; Zeiler, FA; Rostami, E; Tsitsopoulos, P; Stevens, RD; Sahuquillo, J; Payen, J-F; Thelin, E; Sundström, T; de la Lama Zaragoza, A; Younsi, A; Hossain, I; Buki, A; Toth, P; Unterberg, A; Iaccarino, C; Koskinen, L-OD; Grossberg, JA; Lecky, F; Wright, D; Karibe, H; Pinedo Portilla, JL; Maeda, T; El Fiki, A; Gao, G; Lindner, D; Unden, J; Delgado, P; Sakowitz, O; Silvio Taccone, F; Ibañez, J; Suehiro, E; Maas, A; Schuhmann, M; Citerio, G; Ljungqvist, J; Meyfroidt, G; Ratcliff, J; Shabani, HK; Reisner, A; Terpolilli, N; Max Mauer, U; Meixensberger, J; Aarhus, M; Luoto, T; Petr, O; Poca, MA; Ginstman, F; Alén, JAF; Uhl, E; Carbayo, G; Kolias, A (2025) Consensus on the management of traumatic brain injury in older adults: Results from a Delphi study. Brain and Spine, 5. p. 104319. ISSN 2772-5294 https://doi.org/10.1016/j.bas.2025.104319
SGUL Authors: Papadopoulos, Marios

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Abstract

Introduction As the world population is rapidly becoming older, the incidence of traumatic brain injury (TBI) is increasing among older adults with vast implications for brain health of older adults in Europe. Due to differences from younger patients, there are areas of uncertainty in the assessment, diagnosis and management of TBI in older adults. Research question To reach a consensus among experts on statements regarding the definition of old age, assessment, diagnosis and management of traumatic brain injury in older adults. Materials and methods A modified Delphi method consisting of two online rounds was organised, followed by an in-person meeting. Consensus was defined as >75 % agreement. In the second online round the experts were able to view their first assessment and the average of the group. Some statements were rephrased and presented again in the in-person meeting. Questions with numerical data could not be assessed by consensus and descriptive and non-parametric statistics were used to analyze them. Results Experts (n = 72), from different nationalities (Europe, United States, Latin America, Africa and Asia) and specialities (Neurosurgery, Emergency Medicine, Intensive care medicine) responded on 62 statements. Consensus was finally reached on 44 statements regarding the definition of older adulthood, as well as the assessment, surgical and intensive care management, discharge, and rehabilitation of patients. Discussion and conclusions This consensus reinforces the importance of this area for physicians and researchers interested in traumatic brain injury. It signals important areas of agreement as well as future topics for research and specific knowledge gaps.

Item Type: Article
Additional Information: © 2025 The Authors. Published by Elsevier B.V. on behalf of EUROSPINE, the Spine Society of Europe, EANS, the European Association of Neurosurgical Societies. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
SGUL Research Institute / Research Centre: Academic Structure > Neuroscience & Cell Biology Research Institute
Academic Structure > Neuroscience & Cell Biology Research Institute > Neuromodulation & Motor Control
Journal or Publication Title: Brain and Spine
ISSN: 2772-5294
Language: en
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Projects:
Project IDFunderFunder ID
FMM 2023/0108Fundación Mutua Madrileñahttps://doi.org/10.13039/100008061
UNSPECIFIEDSigrid Juséliuksen Säätiöhttps://doi.org/10.13039/501100006306
UNSPECIFIEDResearch Council of Finlandhttps://doi.org/10.13039/501100002341
Dates:
Date Event
2025-07-18 Published
2025-07-11 Published Online
2025-07-02 Accepted
URI: https://openaccess.sgul.ac.uk/id/eprint/118080
Publisher's version: https://doi.org/10.1016/j.bas.2025.104319

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