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Implementation of surgical site infection prophylaxis in children – a cross-sectional prospective study

Paganetti, C; Subotic, U; Sanchez, C; Deak, C; Kusche, R; Autorino, G; Mendoza-Sagaon, M; Pfeifle, VA; Gualtieri, R; Posfay-Barbe, K; et al. Paganetti, C; Subotic, U; Sanchez, C; Deak, C; Kusche, R; Autorino, G; Mendoza-Sagaon, M; Pfeifle, VA; Gualtieri, R; Posfay-Barbe, K; Oppenheim, R; Jauquier, N; Lehner, M; Buettcher, M; Männer, J; Beccarelli, A; Meier, K; Bielicki, JA; Bielicki, IN (2025) Implementation of surgical site infection prophylaxis in children – a cross-sectional prospective study. Journal of Hospital Infection, 162. pp. 360-367. ISSN 0195-6701 https://doi.org/10.1016/j.jhin.2025.03.018
SGUL Authors: Bielicki, Julia Anna

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Abstract

BACKGROUND: Surgical site infections (SSIs) are a common cause of morbidity and mortality in both adults and children. In paediatric surgery, evidence on specific prevention measures is lacking, and practices mainly depend on local guidelines and the preferences of the treating team. AIM: To investigate current practices for children undergoing surgery with respect to SSI prevention using a standardized surveillance tool. METHODS: Nine Swiss paediatric surgery centres participated in a standard period prevalence study. SSI prevention measures were recorded in these hospitals over 7 consecutive days in October 2022 for any paediatric surgical procedure resulting in a surgical wound. The SSI prevention measures of interest were drawn from the most recent World Health Organization guidelines. FINDINGS: In total, 351 procedures were included. All Swiss language regions were represented. Traumatologic/orthopaedic surgeries were most common. Surgical antibiotic prophylaxis was administered in 161/351 (46%) cases, although in 33/161 (21%) cases, there was no indication for the administration of antibiotics. Alcohol-based or iodine-based solutions were most often used for surgical skin preparation. Antimicrobial-coated sutures were only used in 84/351 (24%) cases. Regional differences in prevention measures were noted between participating centres for skin preparation solution, suture material, wound dressing, and implementation of warming devices. CONCLUSION: This study provides an overview of current SSI prevention practices in Swiss paediatric surgery centres, identifies targets for improvement, and highlights areas of clinical uncertainty requiring further investigation. The findings underscore the need for standardized guidelines to ensure consistent and evidence-based SSI prevention strategies in paediatric surgery.

Item Type: Article
Additional Information: © 2025 The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Infection control/methods, Paediatric surgery, Surgical wound infection/prevention and control, Switzerland, Humans, Surgical Wound Infection, Cross-Sectional Studies, Switzerland, Child, Prospective Studies, Child, Preschool, Infant, Male, Female, Adolescent, Antibiotic Prophylaxis, Infant, Newborn
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Journal of Hospital Infection
ISSN: 0195-6701
Language: en
Media of Output: Print-Electronic
Related URLs:
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
UNSPECIFIEDSwiss Clinical Trial OrganizationUNSPECIFIED
PubMed ID: 40339919
Dates:
Date Event
2025-07-14 Published
2025-05-06 Published Online
2025-03-31 Accepted
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/117913
Publisher's version: https://doi.org/10.1016/j.jhin.2025.03.018

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