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Potential activities to reduce the extent of substandard and falsified antibiotics across Africa and associated antimicrobial resistance

Maluleke, TM; Mekonnen, BA; Ubaka, CM; Anand Paramadhas, BD; Munzhedzi, M; Kalungia, AC; Hango, E; Kumar, S; Godman, B; Meyer, JC (2025) Potential activities to reduce the extent of substandard and falsified antibiotics across Africa and associated antimicrobial resistance. Frontiers in Tropical Diseases, 6. p. 1634029. ISSN 2673-7515 https://doi.org/10.3389/fitd.2025.1634029
SGUL Authors: Godman, Brian Barr

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Abstract

Antimicrobial resistance (AMR) is a global public health threat exacerbated by inappropriate antibiotic use. This is particularly important in Africa. The availability of substandard and falsified antibiotics, particularly among African countries, contributes to this adding to the burden of AMR. Poor monitoring and regulatory controls among African countries increases the public health risks of these antibiotics. This is especially the case in the informal sector. Addressing Africa’s battle against substandard and falsified antibiotics requires an integrated approach building on current WHO, Interpol and Pan-African initiatives. Activities include harmonizing regulatory activities across Africa and increasing the monitoring of available antibiotics as well as fines and sanctions for offenders. In addition, reducing the current high levels of inappropriate antibiotic use makes the market for falsified and substandard antibiotics considerably less attractive.

Item Type: Article
Additional Information: Copyright © 2025 Maluleke, Mekonnen, Ubaka, Paramadhas, Munzhedzi, Kalungia, Hango, Kumar, Godman and Meyer. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Frontiers in Tropical Diseases
ISSN: 2673-7515
Publisher License: Creative Commons: Attribution 4.0
Dates:
Date Event
2025-09-24 Published
2025-08-25 Accepted
URI: https://openaccess.sgul.ac.uk/id/eprint/117799
Publisher's version: https://doi.org/10.3389/fitd.2025.1634029

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