Rouse, MA; Ramanan, S; Halai, AD; Volfart, A; Garrard, P; Patterson, K; Rowe, JB; Ralph, MAL
(2024)
The impact of bilateral versus unilateral anterior temporal lobe damage on face recognition, person knowledge and semantic memory.
CEREBRAL CORTEX, 34 (8).
bhae336.
ISSN 1047-3211
https://doi.org/10.1093/cercor/bhae336
SGUL Authors: Garrard, Peter
Abstract
The functional importance of the anterior temporal lobes (ATLs) has come to prominence in two active, albeit unconnected literatures—(i) face recognition and (ii) semantic memory. To generate a unified account of the ATLs, we tested the predictions from each literature and examined the effects of bilateral versus unilateral ATL damage on face recognition, person knowledge, and semantic memory. Sixteen people with bilateral ATL atrophy from semantic dementia (SD), 17 people with unilateral ATL resection for temporal lobe epilepsy (TLE; left = 10, right = 7), and 14 controls completed tasks assessing perceptual face matching, person knowledge and general semantic memory. People with SD were impaired across all semantic tasks, including person knowledge. Despite commensurate total ATL damage, unilateral resection generated mild impairments, with minimal differences between left- and right-ATL resection. Face matching performance was largely preserved but slightly reduced in SD and right TLE. All groups displayed the familiarity effect in face matching; however, it was reduced in SD and right TLE and was aligned with the level of item-specific semantic knowledge in all participants. We propose a neurocognitive framework whereby the ATLs underpin a resilient bilateral representation system that supports semantic memory, person knowledge and face recognition.
Item Type: |
Article
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Additional Information: |
© The Author(s) 2024. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: |
face recognition, person knowledge, prosopagnosia, semantic dementia, temporal lobe epilepsy, 1109 Neurosciences, 1701 Psychology, 1702 Cognitive Sciences, Experimental Psychology |
SGUL Research Institute / Research Centre: |
Academic Structure > REF 2021 user group |
Journal or Publication Title: |
CEREBRAL CORTEX |
ISSN: |
1047-3211 |
Dates: |
Date | Event |
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10 August 2024 | Published | 26 July 2024 | Accepted |
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Publisher License: |
Creative Commons: Attribution 4.0 |
Projects: |
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Web of Science ID: |
WOS:001287333300002 |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/116786 |
Publisher's version: |
https://doi.org/10.1093/cercor/bhae336 |
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