Hasso-Agopsowicz, M;
Sparrow, E;
Cameron, AM;
Sati, H;
Srikantiah, P;
Gottlieb, S;
Bentsi-Enchill, A;
Le Doare, K;
Hamel, M;
Giersing, BK;
et al.
Hasso-Agopsowicz, M; Sparrow, E; Cameron, AM; Sati, H; Srikantiah, P; Gottlieb, S; Bentsi-Enchill, A; Le Doare, K; Hamel, M; Giersing, BK; Hausdorff, WP
(2024)
The role of vaccines in reducing antimicrobial resistance: A review of potential impact of vaccines on AMR and insights across 16 vaccines and pathogens.
Vaccine, 42 (19, Supplement 1).
S1-S8.
ISSN 1873-2518
https://doi.org/10.1016/j.vaccine.2024.06.017
SGUL Authors: Le Doare, Kirsty
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Abstract
In 2019, an estimated 4.95 million deaths were linked to antimicrobial resistance (AMR). Vaccines can prevent many of these deaths by averting both drug-sensitive and resistant infections, reducing antibiotic usage, and lowering the likelihood of developing resistance genes. However, their role in mitigating AMR is currently underutilized. This article builds upon previous research that utilizes Vaccine Value Profiles-tools that assess the health, socioeconomic, and societal impact of pathogens-to inform vaccine development. We analyze the effects of 16 pathogens, covered by Vaccine Value Profiles, on AMR, and explore how vaccines could reduce AMR. The article also provides insights into vaccine development and usage. Vaccines are crucial in lessening the impact of infectious diseases and curbing the development of AMR. To fully realize their potential, vaccines must be more prominently featured in the overall strategy to combat AMR. This requires ongoing investment in research and development of new vaccines and the implementation of additional prevention and control measures to address this global threat effectively.
Item Type: | Article | ||||||||
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Additional Information: | © 2024 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | ||||||||
Keywords: | Antimicrobial resistance, Vaccine value profile, Vaccines, 06 Biological Sciences, 07 Agricultural and Veterinary Sciences, 11 Medical and Health Sciences, Virology | ||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Infection and Immunity Research Institute (INII) Academic Structure > REF 2021 user group |
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Journal or Publication Title: | Vaccine | ||||||||
ISSN: | 1873-2518 | ||||||||
Language: | eng | ||||||||
Dates: |
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Publisher License: | Creative Commons: Attribution 4.0 | ||||||||
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PubMed ID: | 38876836 | ||||||||
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URI: | https://openaccess.sgul.ac.uk/id/eprint/116629 | ||||||||
Publisher's version: | https://doi.org/10.1016/j.vaccine.2024.06.017 |
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