Wadoo, O; Ouanes, S; Firdosi, M
(2021)
Neuroleptic malignant syndrome: a guide for psychiatrists.
BJPsych Advances, 27 (6).
pp. 373-382.
ISSN 2056-4678
https://doi.org/10.1192/bja.2020.71
SGUL Authors: Firdosi, Muhammad Mudasir
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Abstract
Neuroleptic malignant syndrome (NMS) is a rare and potentially fatal adverse reaction to drugs. In psychiatric practice, it is mainly associated with antipsychotics. The classic presentation is that of hyperpyrexia, muscle rigidity, mental state changes and autonomic instability. Subtle forms are difficult to recognise owing to symptom overlap with other conditions. This article discusses the clinical presentation of the syndrome, its differential diagnosis and use of supportive care, medication and electroconvulsive therapy in its treatment. It also explores prevention of NMS and reinstatement of treatment after an episode. It is stressed that all but the mildest forms of NMS should be considered a medical emergency that is properly managed in an acute hospital.
Item Type: | Article | ||||||||
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Additional Information: | This article has been published in a revised form in BJPsych Advances [http://doi.org/10.1192/bja.2020.71]. This version is free to view and download for private research and study only. Not for re-distribution or re-use. © The Authors 2020. | ||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Institute of Medical & Biomedical Education (IMBE) | ||||||||
Journal or Publication Title: | BJPsych Advances | ||||||||
ISSN: | 2056-4678 | ||||||||
Language: | en | ||||||||
Dates: |
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Publisher License: | Publisher's own licence | ||||||||
URI: | https://openaccess.sgul.ac.uk/id/eprint/112837 | ||||||||
Publisher's version: | https://doi.org/10.1192/bja.2020.71 |
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