Magavern, EF; Warren, HR; Ng, FL; Cabrera, CP; Munroe, PB; Caulfield, MJ
(2021)
An Academic Clinician's Road Map to Hypertension Genomics: Recent Advances and Future Directions MMXX.
Hypertension, 77 (2).
pp. 284-295.
ISSN 1524-4563
https://doi.org/10.1161/HYPERTENSIONAHA.120.14535
SGUL Authors: Ng, Fu Liang
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Abstract
At the dawn of the new decade, it is judicious to reflect on the boom of knowledge about polygenic risk for essential hypertension supplied by the wealth of genome-wide association studies. Hypertension continues to account for significant cardiovascular morbidity and mortality, with increasing prevalence anticipated. Here, we overview recent advances in the use of big data to understand polygenic hypertension, as well as opportunities for future innovation to translate this windfall of knowledge into clinical benefit.
Item Type: | Article | ||||||||
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Additional Information: | This is a non-final version of an article published in final form in Magavern, EF; Warren, HR; Ng, FL; Cabrera, CP; Munroe, PB; Caulfield, MJ (2021) An Academic Clinician's Road Map to Hypertension Genomics: Recent Advances and Future Directions MMXX. Hypertension, 77 (2). pp. 284-295. | ||||||||
Keywords: | cardiovascular diseases, genetics, hypertension, risk score, Cardiovascular System & Hematology, 1103 Clinical Sciences, 1102 Cardiorespiratory Medicine and Haematology | ||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Institute of Medical & Biomedical Education (IMBE) | ||||||||
Journal or Publication Title: | Hypertension | ||||||||
ISSN: | 1524-4563 | ||||||||
Language: | eng | ||||||||
Dates: |
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Publisher License: | Publisher's own licence | ||||||||
PubMed ID: | 33390048 | ||||||||
Go to PubMed abstract | |||||||||
URI: | https://openaccess.sgul.ac.uk/id/eprint/112822 | ||||||||
Publisher's version: | https://doi.org/10.1161/HYPERTENSIONAHA.120.14535 |
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