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Grepafloxacin, a dimethyl derivative of ciprofloxacin, acts preferentially through gyrase in Streptococcus pneumoniae: Role of the C-5 group in target specificity

Morris, JE; Pan, XS; Fisher, LM (2002) Grepafloxacin, a dimethyl derivative of ciprofloxacin, acts preferentially through gyrase in Streptococcus pneumoniae: Role of the C-5 group in target specificity. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 46 (2). 582 - 585 (4). ISSN 0066-4804 https://doi.org/10.1128/AAC.46.2.582-585.2002
SGUL Authors: Fisher, Larry Mark Pan, Xiao Su

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Item Type: Article
Additional Information: PubMed ID: 11796384
Keywords: Science & Technology, Life Sciences & Biomedicine, Microbiology, Pharmacology & Pharmacy, DNA GYRASE, TOPOISOMERASE-IV, IN-VITRO, FLUOROQUINOLONE RESISTANCE, II TOPOISOMERASES, PARC, GEMIFLOXACIN, PURIFICATION, INHIBITION, QUINOLONES, Anti-Infective Agents, Ciprofloxacin, DNA Gyrase, Drug Delivery Systems, Fluoroquinolones, Molecular Conformation, Piperazines, Streptococcus pneumoniae
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) > Cell Sciences (INCCCS)
Journal or Publication Title: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN: 0066-4804
Related URLs:
Web of Science ID: WOS:000173427900056
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URI: https://openaccess.sgul.ac.uk/id/eprint/299
Publisher's version: https://doi.org/10.1128/AAC.46.2.582-585.2002

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