Jones, AM;
Beggs, AD;
Carvajal-Carmona, L;
Farrington, S;
Tenesa, A;
Walker, M;
Howarth, K;
Ballereau, S;
Hodgson, SV;
Zauber, A;
et al.
Jones, AM; Beggs, AD; Carvajal-Carmona, L; Farrington, S; Tenesa, A; Walker, M; Howarth, K; Ballereau, S; Hodgson, SV; Zauber, A; Bertagnolli, M; Midgley, R; Campbell, H; Kerr, D; Dunlop, MG; Tomlinson, IP
(2012)
TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres.
Gut, 61 (2).
248 - 254.
https://doi.org/10.1136/gut.2011.239772
SGUL Authors: Hodgson, Shirley Victoria
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Abstract
Shorter telomeres have been associated with increased risk of malignancy, including colorectal cancer (CRC). Telomere length is heritable and may be an intermediate phenotype linked to genetic susceptibility to CRC.
| Item Type: |
Article
|
| Additional Information: |
PMCID: PMC3245900 |
| Keywords: |
Adenoma, Aged, Carcinoma, Case-Control Studies, Colorectal Neoplasms, Female, Genetic Predisposition to Disease, Genotyping Techniques, HCT116 Cells, Humans, Leukocytes, Male, Middle Aged, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, RNA, Retrospective Studies, Telomerase, Telomere |
| SGUL Research Institute / Research Centre: |
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) > Cell Sciences (INCCCS) |
| Journal or Publication Title: |
Gut |
| Dates: |
| Date | Event |
|---|
| February 2012 | Published |
|
| PubMed ID: |
21708826 |
| Web of Science ID: |
21708826 |
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Go to PubMed abstract |
| URI: |
https://openaccess.sgul.ac.uk/id/eprint/1905 |
| Publisher's version: |
https://doi.org/10.1136/gut.2011.239772 |
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