Savarese, G;
Lindberg, F;
Cannata, A;
Adamo, M;
Ambrosio, G;
Ameri, P;
Anker, MS;
Bäck, M;
Bayes‐Genis, A;
Ben Gal, T;
et al.
Savarese, G; Lindberg, F; Cannata, A; Adamo, M; Ambrosio, G; Ameri, P; Anker, MS; Bäck, M; Bayes‐Genis, A; Ben Gal, T; Braunschweig, F; Chioncel, O; D'Elia, E; El‐Tamimi, H; Filippatos, G; Girerd, N; Hill, L; Jankowska, E; Khunti, K; Lewis, BS; Moura, B; Amir, O; Paolillo, S; Piepoli, M; Shehab, A; Simpson, M; Skouri, H; Stolfo, D; Tocchetti, CG; Vitale, C; Volterrani, M; von Haehling, S; Wassmann, S; Yilmaz, MB; Kaski, JC; Dobrev, D; Metra, M; Rosano, GMC
(2025)
Adherence to Guideline-Directed Medical Treatments in Heart Failure. A Scientific Statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Cardiovascular Pharmacotherapy.
European Journal of Heart Failure, 27 (12).
pp. 2716-2731.
ISSN 1388-9842
https://doi.org/10.1002/ejhf.70090
SGUL Authors: Kaski, Juan Carlos
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Abstract
Heart failure (HF) affects over 60 million individuals globally. Contemporary guideline‐directed medical therapies (GDMT) reduce cardiovascular mortality and HF hospitalizations. However, medication non‐adherence represents a critical barrier limiting real‐world efficacy of GDMT. This scientific statement aims to provide a comprehensive framework for understanding, measuring, and addressing medication non‐adherence in HF management across diverse healthcare settings. Addressing medication non‐adherence requires systematic, multifaceted approaches targeting individual patient barriers while implementing system‐level interventions. Polypills, digital monitoring platforms, enhanced patient education and empowerment, and multidisciplinary care models represent promising strategies to optimize therapeutic adherence and improve clinical outcomes in HF management.
| Item Type: | Article | |||||||||||||||||||||||||||||||||
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| Additional Information: | © 2025 The Author(s). European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial https://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. | |||||||||||||||||||||||||||||||||
| Keywords: | Adherence, Digital, Education, Fixed‐dose combinations, Guidelines, Heart failure, Multidisciplinary, Polypill, Humans, Heart Failure, Guideline Adherence, Cardiovascular Agents, Societies, Medical, Medication Adherence, Cardiology, Practice Guidelines as Topic | |||||||||||||||||||||||||||||||||
| SGUL Research Institute / Research Centre: | Academic Structure > Cardiovascular & Genomics Research Institute Academic Structure > Cardiovascular & Genomics Research Institute > Clinical Cardiology |
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| Journal or Publication Title: | European Journal of Heart Failure | |||||||||||||||||||||||||||||||||
| ISSN: | 1388-9842 | |||||||||||||||||||||||||||||||||
| Language: | en | |||||||||||||||||||||||||||||||||
| Media of Output: | Print-Electronic | |||||||||||||||||||||||||||||||||
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| Publisher License: | Creative Commons: Attribution-Noncommercial 4.0 | |||||||||||||||||||||||||||||||||
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| URI: | https://openaccess.sgul.ac.uk/id/eprint/118250 | |||||||||||||||||||||||||||||||||
| Publisher's version: | https://doi.org/10.1002/ejhf.70090 |
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