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Survival rates of cervical cancer patients in Sarawak: a single-centre referral study

Lim, MSH; Tan, SSN; Wan Maharuddin, IB; Voon, PJ; Abdul Rahim, NKB; Tiong, XT; Chee, CSM; Ismail, AM; Augustin, Y (2025) Survival rates of cervical cancer patients in Sarawak: a single-centre referral study. BMC Cancer, 25 (1). p. 1381. ISSN 1471-2407 https://doi.org/10.1186/s12885-025-14678-9
SGUL Authors: Augustin, Yolanda Sydney

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Abstract

BACKGROUND: Cervical cancer represents a significant health challenge in Malaysia, especially in the state of Sarawak which records some of the highest incidence rates across the country. This study evaluates the survival rates of cervical cancer patients in Sarawak, focusing on demographic characteristics, disease stage and survival outcomes to inform healthcare strategies. METHODS: A retrospective case notes review of disease stage, patterns of care and survival outcomes of patients diagnosed with cervical cancer at Sarawak General Hospital between January 2018 to December 2022 was conducted. Kaplan-Meier survival analysis and Cox Regression analysis were performed to assess survival outcomes and factors influencing survival. RESULTS: A total of 555 patients were included in this review. The majority of patients were diagnosed between the ages of 40 and 59, with a mean age of 53 years. Ibans comprised the largest subgroup by ethnicity. Only 11.2% of patients were diagnosed with Stage I disease. The majority of patients were diagnosed at advanced stages III and IV. The overall 5-year survival rate was 59.4%. Factors significantly affecting survival included FIGO cancer stage and ethnicity. CONCLUSIONS: Diagnosis at advanced stages of disease lead to poorer clinical outcomes in cervical cancer patients in Sarawak. This study highlights the critical need for enhanced screening and early diagnosis to improve survival rates amongst cervical cancer patients Sarawak. Efforts should focus on improving cervical health literacy, expanding access to healthcare services and improving the uptake of HPV vaccination and cervical screening particularly in rural communities.

Item Type: Article
Additional Information: © The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: Cervical cancer, Epidemiology, Sarawak, Survival analysis
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: BMC Cancer
ISSN: 1471-2407
Language: en
Media of Output: Electronic
Related URLs:
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
IRG/F05/ROCHE/86395/2024Roche (Malaysia Sdn Bhd)UNSPECIFIED
UNSPECIFIEDSociety for Cancer Advocacy and Awareness (SCAN) KuchingUNSPECIFIED
UNI/F05/VC-HIRG/85521/P13-03/2022VC High Impact Grant UNIMASUNSPECIFIED
Dates:
Date Event
2025-08-27 Published
2025-07-11 Accepted
URI: https://openaccess.sgul.ac.uk/id/eprint/117855
Publisher's version: https://doi.org/10.1186/s12885-025-14678-9

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