Thorn, N; Karampatsas, K; Le Doare, K; Heath, PT
(2025)
Progress towards a Group B streptococcal vaccine – where are we now?
Vaccine, 62.
p. 127575.
ISSN 0264-410X
https://doi.org/10.1016/j.vaccine.2025.127575
SGUL Authors: Thorn, Natasha Louise
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Abstract
The global burden of Group B streptococcal (GBS) disease remains high and an effective vaccine in pregnancy is an unmet public health need. GBS vaccines have been in development for decades, with earlier work providing evidence of immunogenicity and safety but not resulting in a licensed product. More recently, two vaccine candidates have reached advanced stages of clinical development. This article reviews the progress towards a GBS vaccine, the challenges that lie ahead and how they might be overcome.
| Item Type: | Article |
|---|---|
| Additional Information: | © 2025 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/). |
| SGUL Research Institute / Research Centre: | Academic Structure > Infection and Immunity Research Institute (INII) |
| Journal or Publication Title: | Vaccine |
| ISSN: | 0264-410X |
| Language: | en |
| Publisher License: | Creative Commons: Attribution-Noncommercial 4.0 |
| URI: | https://openaccess.sgul.ac.uk/id/eprint/117787 |
| Publisher's version: | https://doi.org/10.1016/j.vaccine.2025.127575 |
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