Abstract

Background: Antibiotic shortages in public hospitals across sub-Saharan Africa represent a growing public health crisis increasing antimicrobial resistance (AMR). While European countries have conducted several surveys on medicine shortages, similar data is scarce in sub-Saharan Africa. Ensuring the availability of critical antibiotics among hospitals across Africa is essential for effective treatment of infectious diseases and for implementing targeted antimicrobial stewardship programmes (ASPs) to reduce AMR. Objective: To evaluate the scope, causes and potential solutions regarding antibiotic shortages in public sector hospitals across sub-Saharan Africa. Subsequently, use the findings to make recommendations for future strategies including ASPs. Methods: A cross-sectional descriptive survey will be undertaken among hospital pharmacists, nurses, physicians, and other healthcare professionals across sub-Saharan Africa. An electronic questionnaire, based on the EAHP model and available in English, French, and Portuguese, will gather data on the frequency, types, causes, and proposed solutions to antibiotic shortages in hospitals. The survey will run for two months, leveraging existing professional networks to enhance participation. Open ended responses will be processed in Excel with descriptive statistics, including frequencies, percentages, means, and standard deviations, will be calculated using STATA® to summarize both categorical and continuous variables. Discussion and Conclusions: This study will provide comprehensive data on the prevalence and drivers of antibiotic shortages in public hospitals in this important region. The findings will inform national and regional health policies, strengthen supply chain resilience, and support ASP implementation. This will be the first time that such a comprehensive survey will be conducted across sub-Saharan Africa.