Zoumprouli, A; Carden, R; Bilotta, F
(2025)
Current and novel approaches for critical care management of aneurysmal subarachnoid hemorrhage in critical care.
Current Opinion in Anaesthesiology.
ISSN 0952-7907
https://doi.org/10.1097/aco.0000000000001533
SGUL Authors: Zoumprouli, Argyro
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Abstract
Purpose of the review This review highlights recent advancements and evidence-based approaches in the critical care management of aneurysmal subarachnoid hemorrhage (aSAH), focusing on developments from the past 18 months. It addresses key challenges [rebleeding prevention, delayed cerebral ischemia (DCI), hydrocephalus, transfusion strategies, and temperature management], emphasizing multidisciplinary care and personalized treatment. Recent findings Recent studies underscore the importance of systolic blood pressure control (<160 mmHg) to reduce rebleeding risk before aneurysm securing. Novel prognostic tools, including the modified 5-item frailty index and quantitative imaging software, show promise in improving outcome prediction. Prophylactic lumbar drainage may reduce DCI and improve neurological outcomes, while milrinone and computed tomography perfusion-guided therapies are being explored for vasospasm management. Transfusion strategies suggest a hemoglobin threshold of 9 g/dl may optimize outcomes. Temperature management remains contentious, but consensus recommends maintaining normothermia (36.0–37.5 °C) with continuous monitoring. Summary Advances in aSAH care emphasize precision medicine, leveraging technology [e.g. Artificial intelligence (AI), quantitative imaging], and multidisciplinary collaboration. Key unresolved questions warrant multicenter trials to validate optimal blood pressure, transfusion, and temperature targets alongside emerging therapies for DCI.
Item Type: | Article |
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Additional Information: | This is a non-final version of an article published in final form in Zoumprouli, A; Carden, R; Bilotta, F (2025) Current and novel approaches for critical care management of aneurysmal subarachnoid hemorrhage in critical care. Current Opinion in Anaesthesiology. |
SGUL Research Institute / Research Centre: | Academic Structure > Neuroscience & Cell Biology Research Institute |
Journal or Publication Title: | Current Opinion in Anaesthesiology |
ISSN: | 0952-7907 |
Language: | en |
Publisher License: | Publisher's own licence |
URI: | https://openaccess.sgul.ac.uk/id/eprint/117673 |
Publisher's version: | https://doi.org/10.1097/aco.0000000000001533 |
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