SORA

Advancing, promoting and sharing knowledge of health through excellence in teaching, clinical practice and research into the prevention and treatment of illness

Current and novel approaches for critical care management of aneurysmal subarachnoid hemorrhage in critical care

Zoumprouli, A; Carden, R; Bilotta, F (2025) Current and novel approaches for critical care management of aneurysmal subarachnoid hemorrhage in critical care. Current Opinion in Anaesthesiology. ISSN 0952-7907 https://doi.org/10.1097/aco.0000000000001533
SGUL Authors: Zoumprouli, Argyro

[img] Microsoft Word (.docx) Accepted Version
Restricted to Repository staff only until 3 June 2026.
Available under License ["licenses_description_publisher" not defined].

Download (71kB)

Abstract

Purpose of the review This review highlights recent advancements and evidence-based approaches in the critical care management of aneurysmal subarachnoid hemorrhage (aSAH), focusing on developments from the past 18 months. It addresses key challenges [rebleeding prevention, delayed cerebral ischemia (DCI), hydrocephalus, transfusion strategies, and temperature management], emphasizing multidisciplinary care and personalized treatment. Recent findings Recent studies underscore the importance of systolic blood pressure control (<160 mmHg) to reduce rebleeding risk before aneurysm securing. Novel prognostic tools, including the modified 5-item frailty index and quantitative imaging software, show promise in improving outcome prediction. Prophylactic lumbar drainage may reduce DCI and improve neurological outcomes, while milrinone and computed tomography perfusion-guided therapies are being explored for vasospasm management. Transfusion strategies suggest a hemoglobin threshold of 9 g/dl may optimize outcomes. Temperature management remains contentious, but consensus recommends maintaining normothermia (36.0–37.5 °C) with continuous monitoring. Summary Advances in aSAH care emphasize precision medicine, leveraging technology [e.g. Artificial intelligence (AI), quantitative imaging], and multidisciplinary collaboration. Key unresolved questions warrant multicenter trials to validate optimal blood pressure, transfusion, and temperature targets alongside emerging therapies for DCI.

Item Type: Article
Additional Information: This is a non-final version of an article published in final form in Zoumprouli, A; Carden, R; Bilotta, F (2025) Current and novel approaches for critical care management of aneurysmal subarachnoid hemorrhage in critical care. Current Opinion in Anaesthesiology.
SGUL Research Institute / Research Centre: Academic Structure > Neuroscience & Cell Biology Research Institute
Journal or Publication Title: Current Opinion in Anaesthesiology
ISSN: 0952-7907
Language: en
Publisher License: Publisher's own licence
URI: https://openaccess.sgul.ac.uk/id/eprint/117673
Publisher's version: https://doi.org/10.1097/aco.0000000000001533

Actions (login required)

Edit Item Edit Item