Baldomero, H;
Neumann, D;
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(2024)
The role of registries in hematological disorders.
Best Pract Res Clin Haematol, 37 (2).
p. 101556.
ISSN 1521-6926
https://doi.org/10.1016/j.beha.2024.101556
SGUL Authors: Koh, Mickey
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Abstract
Hematopoietic cell transplantation (HCT) was developed more than 65 years ago to treat malignant blood disorders and irreversible bone marrow failures, with the aim of replacing a diseased hematopoietic system with a healthy one (allogeneic HCT). Decades later, the procedure was adapted to apply maximal chemotherapy or radiotherapy, which would result in bone marrow failure, but could be remedied by an infusion of a patient's own cryopreserved bone marrow (autologous HCT). Both treatments are high-risk and complex, especially during the initial phases. However, concerted efforts, vision, and collaboration between physicians and centers worldwide have resulted in HCT becoming a standard of care for many hematological disorders with progressive improvements in outcomes. Registries and the collaboration of societies worldwide have enabled the delivery of this curative therapy to many patients with fatal hematological diseases. More than 1.5 million HCT were performed between 1957 and 2019, and activity is continuously increasing worldwide.
Item Type: | Article | ||||||
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Additional Information: | © 2024 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | ||||||
Keywords: | Allogeneic HCT, Autologous HCT, Hematopoietic cell transplantation (HCT), Leukemia, Outcome registry, Registries, Survey, Humans, Registries, Hematopoietic Stem Cell Transplantation, Hematologic Diseases | ||||||
SGUL Research Institute / Research Centre: | Academic Structure > Institute of Medical, Biomedical and Allied Health Education (IMBE) | ||||||
Journal or Publication Title: | Best Pract Res Clin Haematol | ||||||
ISSN: | 1521-6926 | ||||||
Language: | eng | ||||||
Media of Output: | Print-Electronic | ||||||
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Publisher License: | Creative Commons: Attribution 4.0 | ||||||
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PubMed ID: | 39098798 | ||||||
Go to PubMed abstract | |||||||
URI: | https://openaccess.sgul.ac.uk/id/eprint/117449 | ||||||
Publisher's version: | https://doi.org/10.1016/j.beha.2024.101556 |
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