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An outbreak caused by the SARS-CoV-2 Delta (B.1.617.2) variant in a care home after partial vaccination with a single dose of the COVID-19 vaccine Vaxzevria, London, England, April 2021.

Williams, SV; Vusirikala, A; Ladhani, SN; Fernandez Ruiz De Olano, E; Iyanger, N; Aiano, F; Stoker, K; Gopal Rao, G; John, L; Patel, B; et al. Williams, SV; Vusirikala, A; Ladhani, SN; Fernandez Ruiz De Olano, E; Iyanger, N; Aiano, F; Stoker, K; Gopal Rao, G; John, L; Patel, B; Andrews, N; Dabrera, G; Ramsay, M; Brown, KE; Lopez Bernal, J; Saliba, V (2021) An outbreak caused by the SARS-CoV-2 Delta (B.1.617.2) variant in a care home after partial vaccination with a single dose of the COVID-19 vaccine Vaxzevria, London, England, April 2021. Euro Surveill, 26 (27). ISSN 1560-7917 https://doi.org/10.2807/1560-7917.ES.2021.26.27.2100626
SGUL Authors: Ladhani, Shamez Nizarali

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Abstract

We investigated a COVID-19 outbreak of the SARS-CoV-2 Delta variant of concern in a London care home, where 8/21 residents and 14/21 staff had received a single dose of Vaxzevria (ChAdOx1-S; AstraZeneca) vaccine. We identified 24 SARS-CoV-2 infections (16 residents, 8 staff) among 40 individuals (19 residents, 21 staff); four (3 residents, 1 staff) were hospitalised, and none died. The attack rate after one vaccine dose was 35.7% (5/14) for staff and 81.3% (13/16) for residents.

Item Type: Article
Additional Information: This work is licensed under a Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/).
Keywords: B.1.617.2 variant, COVID-19, ChAdOx1 vaccine, Delta variant, SARS-CoV-2, Vaxzevria, care home outbreaks, vaccine effectiveness, COVID-19, COVID-19 Vaccines, Disease Outbreaks, England, Humans, London, SARS-CoV-2, Vaccination, Humans, Vaccination, Disease Outbreaks, London, England, COVID-19, SARS-CoV-2, COVID-19 Vaccines, 0605 Microbiology, 1117 Public Health and Health Services, 1199 Other Medical and Health Sciences
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Euro Surveill
ISSN: 1560-7917
Language: eng
Publisher License: Creative Commons: Attribution 4.0
PubMed ID: 34240699
Web of Science ID: WOS:000672156300003
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/117294
Publisher's version: https://doi.org/10.2807/1560-7917.ES.2021.26.27.2100626

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