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Up-regulated matrix metalloproteinase activity in soil-transmitted helminth-tuberculosis co-infection is associated with increased lung pathology.

Loader, M-CI; Vasquez Alves, S; Gilman, RH; Coronel, J; Taquiri, C; Vasquez Alves, N; Díaz-Soria, F; Durand, S; Kelleher, ST; Jacob, T; et al. Loader, M-CI; Vasquez Alves, S; Gilman, RH; Coronel, J; Taquiri, C; Vasquez Alves, N; Díaz-Soria, F; Durand, S; Kelleher, ST; Jacob, T; Elson, WH; Kirwan, DE; Friedland, JS (2025) Up-regulated matrix metalloproteinase activity in soil-transmitted helminth-tuberculosis co-infection is associated with increased lung pathology. Eur Respir J, 65 (1). p. 2401445. ISSN 1399-3003 https://doi.org/10.1183/13993003.01445-2024
SGUL Authors: Friedland, Jonathan Samuel Loader, Maria Cristina Irene

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Abstract

Individuals with soil-transmitted helminth (STH) infection are more likely to have active pulmonary TB. Both TB and STH infections are independently associated with elevated plasma MMPs, which correlate with worse lung pathology. https://bit.ly/3VgGWjm

Item Type: Article
Additional Information: Copyright ©The authors 2025. This version is distributed under the terms of the Creative Commons Attribution Licence 4.0.
Keywords: 11 Medical and Health Sciences, Respiratory System
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Eur Respir J
ISSN: 1399-3003
Language: eng
Dates:
DateEvent
30 January 2025Published
27 November 2024Accepted
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
UNSPECIFIEDWellcome Trusthttp://dx.doi.org/10.13039/100004440
MR/N001192/1Medical Research Councilhttp://dx.doi.org/10.13039/501100000265
PubMed ID: 39884753
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/117161
Publisher's version: https://doi.org/10.1183/13993003.01445-2024

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