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Anxiety, depression, and perceived wellbeing in antenatal women at risk of preterm birth: a retrospective cohort study.

Worrall, S; Christiansen, P; Carlisle, N; Fallon, V; Khalil, A; Shennan, AH; Tribe, RM; Carter, J; Silverio, SA; UK Preterm Clinical Network (2024) Anxiety, depression, and perceived wellbeing in antenatal women at risk of preterm birth: a retrospective cohort study. Front Glob Womens Health, 5. p. 1511352. ISSN 2673-5059 https://doi.org/10.3389/fgwh.2024.1511352
SGUL Authors: Khalil, Asma

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Abstract

INTRODUCTION: Women identified at risk for preterm may be vulnerable to developing mental health difficulties due to the increased likelihood of poor pregnancy outcome and uncertainty surrounding their delivery. Formal assessment of mental wellbeing in specialist preterm birth clinics is not routinely offered, but may offer the opportunity for early intervention. METHODS: We aimed to investigate if demographic characteristics and obstetric risk factors were associated with psychological wellbeing in women at risk of preterm birth. We explored associations between mental wellbeing and risk factors for preterm birth using hierarchical regression analyses. RESULTS: When demographic variables were considered alone, high body mass index (BMI) was significantly associated with anxiety (p = .026), however became non-significant when obstetric risk factors were also considered. Previous late miscarriage was associated with high anxiety (p = .049). Lower maternal age at estimated date of delivery (p = .019) and non-European ethnic heritage (p = .029) were significantly associated with depression. High maternal BMI (p < .001), being of any other non-European ethnic heritage (p = .043), currently smoking (p = .002), and previous spontaneous preterm birth (p = .017) were associated with lower perceived wellbeing. DISCUSSION: The results of this study highlight the importance of routinely monitoring mental health in women with relevant risk factors, particularly if they are already at risk of preterm birth.

Item Type: Article
Additional Information: Copyright: © 2024 Worrall, Christiansen, Carlisle, Fallon, Khalil, Shennan, Tribe, Carter, Silverio and The UK Preterm Clinical Network. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: antenatal anxiety, antenatal depression, mental health, pregnancy, preterm birth, wellbeing, UK Preterm Clinical Network, antenatal anxiety, antenatal depression, preterm birth, pregnancy, wellbeing, mental health
SGUL Research Institute / Research Centre: Academic Structure > Cardiovascular & Genomics Research Institute
Academic Structure > Cardiovascular & Genomics Research Institute > Vascular Biology
Journal or Publication Title: Front Glob Womens Health
ISSN: 2673-5059
Language: eng
Dates:
DateEvent
6 December 2024Published
25 November 2024Accepted
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
UNSPECIFIEDUniversity Of Liverpoolhttp://dx.doi.org/10.13039/501100000836
UNSPECIFIEDTommy's CharityUNSPECIFIED
PubMed ID: 39713064
Web of Science ID: WOS:001381144600001
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/117062
Publisher's version: https://doi.org/10.3389/fgwh.2024.1511352

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