Vitale, C; Spoletini, I; Rosano, GMC
(2024)
The Dual Burden of Frailty and Heart Failure.
Int J Heart Fail, 6 (3).
pp. 107-116.
ISSN 2636-1558
https://doi.org/10.36628/ijhf.2023.0057
SGUL Authors: Rosano, Giuseppe Massimo Claudio
Abstract
Frailty is highly prevalent among patients with heart failure (HF) and independently predicts adverse outcomes. However, optimal frailty definitions, assessments, and management in HF remain unclear. Frailty is common in HF, affecting up to 80% of patients depending on population characteristics. Even pre-frailty doubles mortality risk versus robust patients. Frailty worsens HF prognosis through systemic inflammation, neurohormonal changes, sarcopenia, and micronutrient deficiency. Simple screening tools like gait speed and grip strength predict outcomes but lack HF-specificity. Comprehensive geriatric assessment is ideal but not always feasible. Exercise, nutrition, poly-pharmacy management, and multidisciplinary care models can help stablize frailty components and improve patient-centred outcomes. Frailty frequently coexists with and exacerbates HF. Routine frailty screening should guide supportive interventions to optimize physical, cognitive, and psychosocial health. Further research on HF-specific frailty assessment tools and interventions is warranted to reduce this dual burden.
Item Type: |
Article
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Additional Information: |
Copyright © 2024. Korean Society of Heart Failure
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: |
Frailty, Heart failure, Prognosis, Rehabilitation, Therapy |
SGUL Research Institute / Research Centre: |
Academic Structure > REF 2021 user group |
Journal or Publication Title: |
Int J Heart Fail |
ISSN: |
2636-1558 |
Language: |
eng |
Dates: |
Date | Event |
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July 2024 | Published | 15 April 2024 | Published Online | 8 April 2024 | Accepted |
|
Publisher License: |
Creative Commons: Attribution-Noncommercial 4.0 |
Projects: |
Project ID | Funder | Funder ID |
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20/1819 | Italian Ministry of Health | UNSPECIFIED |
|
PubMed ID: |
39081645 |
![](http://static.pubmed.gov/portal/portal3rc.fcgi/2745237/img/27842) |
Go to PubMed abstract |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/116743 |
Publisher's version: |
https://doi.org/10.36628/ijhf.2023.0057 |
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