Putowski, Z;
Czok, M;
Polok, K;
Guidet, B;
Jung, C;
Bruno, RR;
de Lange, D;
Leaver, S;
Moreno, R;
Wernly, B;
et al.
Putowski, Z; Czok, M; Polok, K; Guidet, B; Jung, C; Bruno, RR; de Lange, D; Leaver, S; Moreno, R; Wernly, B; Flaatten, H; Szczeklik, W
(2023)
Reporting SOFA in research: we should always present each of the SOFA subscores.
Anaesthesiol Intensive Ther, 55 (5).
pp. 326-329.
ISSN 1731-2531
https://doi.org/10.5114/ait.2023.134188
SGUL Authors: Leaver, Susannah Kiran
Abstract
INTRODUCTION: The Sequential Organ Failure Assessment (SOFA) score is the sum of 6 components, each representing one organ system with dysfunction classified on a 4-point scale. In research, usually by default, the total SOFA score is taken into account, but it may not reflect the severity of the condition of the individual organs. Often, these values are expected to predict mortality. MATERIAL AND METHODS: In this study, we reanalysed 2 cohorts of critically ill elderly patients to explore the distribution of SOFA subscores and to assess the between-group differences. Both cohorts were adjusted to maintain similarity in terms of age and the primary cause of admission (respiratory cause). RESULTS: In total, 910 (non-COVID-19 cohort) and 551 patients (COVID-19 cohort) were included in the analysis. Both cohorts were similar in terms of the total SOFA score (median 5 vs. 5 points); however, the groups differed significantly in 4/6 SOFA subscores (respiratory, neurological, cardiovascular, and coagulation subscores). Moreover, the cohorts had different fractions of organ failures (defined as a SOFA subscore ≥ 3). CONCLUSIONS: This analysis revealed significant differences in SOFA subscores between the COVID-19 and non-COVID-19 respiratory cohorts, highlighting the importance of considering individual organ dysfunction rather than relying solely on the total SOFA score when reporting organ dysfunction in clinical research.
Item Type: |
Article
|
Additional Information: |
Copyright: © Polish Society of Anaesthesiology and Intensive Therapy. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
Keywords: |
SOFA score, multiorgan dysfunction, organ failure, Sequential Organ Failure Assessment, Humans, Aged, Multiple Organ Failure, Organ Dysfunction Scores, Hospital Mortality, Hospitalization, COVID-19, Prognosis, Retrospective Studies, Intensive Care Units, Humans, Multiple Organ Failure, Prognosis, Hospitalization, Hospital Mortality, Retrospective Studies, Aged, Intensive Care Units, Organ Dysfunction Scores, COVID-19 |
SGUL Research Institute / Research Centre: |
Academic Structure > Institute of Medical & Biomedical Education (IMBE) |
Journal or Publication Title: |
Anaesthesiol Intensive Ther |
ISSN: |
1731-2531 |
Language: |
eng |
Dates: |
Date | Event |
---|
30 December 2023 | Published | 13 November 2023 | Accepted |
|
Publisher License: |
Creative Commons: Attribution-Noncommercial-Share Alike 4.0 |
PubMed ID: |
38282498 |
![](http://static.pubmed.gov/portal/portal3rc.fcgi/2745237/img/27842) |
Go to PubMed abstract |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/116498 |
Publisher's version: |
https://doi.org/10.5114/ait.2023.134188 |
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