Zanichelli, V;
Sharland, M;
Cappello, B;
Moja, L;
Getahun, H;
Pessoa-Silva, C;
Sati, H;
van Weezenbeek, C;
Balkhy, H;
Simão, M;
et al.
Zanichelli, V; Sharland, M; Cappello, B; Moja, L; Getahun, H; Pessoa-Silva, C; Sati, H; van Weezenbeek, C; Balkhy, H; Simão, M; Gandra, S; Huttner, B
(2023)
The WHO AWaRe (Access, Watch, Reserve) antibiotic book and prevention of antimicrobial resistance.
Bull World Health Organ, 101 (4).
pp. 290-296.
ISSN 1564-0604
https://doi.org/10.2471/BLT.22.288614
SGUL Authors: Sharland, Michael Roy
Abstract
Guidance on the appropriate use of antibiotics for common infections is lacking in many settings. The World Health Organization (WHO) has recently released The WHO AWaRe (Access, Watch, Reserve) antibiotic book which complements the WHO Model list of essential medicines and WHO Model list of essential medicines for children. The book gives specific guidance on the empiric use of antibiotics in the model lists with a strong emphasis on the AWaRe framework, which is centred around the risk of antimicrobial resistance development associated with the use of different antibiotics. Recommendations in the book cover 34 common infections in primary and hospital care both for children and adults. The book also includes a section on the use of the last-resort Reserve antibiotics, whose use should be restricted to very selected cases when an infection is confirmed or suspected to be caused by multidrug-resistant pathogens. The book highlights the use of first-line Access antibiotics or no antibiotic care if this is the safest approach for the patient. Here we present the background behind the development of the AWaRe book and the evidence behind its recommendations. We also outline how the book could be used in different settings to help reach the WHO target of increasing the proportion of global consumption of Access antibiotics to at least 60% of total consumption. The guidance in the book will also more broadly contribute to improving universal health coverage.
Item Type: |
Article
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Additional Information: |
Copyright (c) 2023 The authors; licensee World Health Organization.
This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL. |
Keywords: |
Child, Humans, Anti-Bacterial Agents, Drug Resistance, Bacterial, World Health Organization, Drugs, Essential, Humans, Drugs, Essential, Anti-Bacterial Agents, Drug Resistance, Bacterial, Child, World Health Organization, 11 Medical and Health Sciences, Tropical Medicine |
SGUL Research Institute / Research Centre: |
Academic Structure > Infection and Immunity Research Institute (INII) |
Journal or Publication Title: |
Bull World Health Organ |
ISSN: |
1564-0604 |
Language: |
eng |
Dates: |
Date | Event |
---|
1 April 2023 | Published | 10 February 2023 | Published Online | 3 January 2023 | Accepted |
|
Publisher License: |
Creative Commons: Attribution 3.0 IGO |
PubMed ID: |
37008270 |
![](http://static.pubmed.gov/portal/portal3rc.fcgi/2745237/img/27842) |
Go to PubMed abstract |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/115493 |
Publisher's version: |
https://doi.org/10.2471/BLT.22.288614 |
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