Bhatia, RT;
Malhotra, A;
MacLachlan, H;
Gati, S;
Marwaha, S;
Chatrath, N;
Fyyaz, S;
Aleixo, H;
Al-Turaihi, S;
Babu, A;
et al.
Bhatia, RT; Malhotra, A; MacLachlan, H; Gati, S; Marwaha, S; Chatrath, N; Fyyaz, S; Aleixo, H; Al-Turaihi, S; Babu, A; Basu, J; Catterson, P; Cooper, R; Daems, JJN; Dhutia, H; Ferrari, F; van Hattum, JC; Iqbal, Z; Kasiakogias, A; Kenny, A; Khanbhai, T; Khoury, S; Miles, C; Oxborough, D; Quazi, K; Rakhit, D; Sharma, A; Varnava, A; Tome Esteban, MT; Finocchiaro, G; Stein, R; Jorstad, HT; Papadakis, M; Sharma, S
(2023)
Prevalence and diagnostic significance of de-novo 12-lead ECG changes after COVID-19 infection in elite soccer players.
Heart, 109 (12).
pp. 936-943.
ISSN 1468-201X
https://doi.org/10.1136/heartjnl-2022-322211
SGUL Authors: Malhotra, Aneil Sharma, Sanjay Tome, Maria Teresa
Abstract
BACKGROUND AND AIM: The efficacy of pre-COVID-19 and post-COVID-19 infection 12-lead ECGs for identifying athletes with myopericarditis has never been reported. We aimed to assess the prevalence and significance of de-novo ECG changes following COVID-19 infection. METHODS: In this multicentre observational study, between March 2020 and May 2022, we evaluated consecutive athletes with COVID-19 infection. Athletes exhibiting de-novo ECG changes underwent cardiovascular magnetic resonance (CMR) scans. One club mandated CMR scans for all players (n=30) following COVID-19 infection, despite the absence of cardiac symptoms or de-novo ECG changes. RESULTS: 511 soccer players (median age 21 years, IQR 18-26 years) were included. 17 (3%) athletes demonstrated de-novo ECG changes, which included reduction in T-wave amplitude in the inferior and lateral leads (n=5), inferior leads (n=4) and lateral leads (n=4); inferior T-wave inversion (n=7); and ST-segment depression (n=2). 15 (88%) athletes with de-novo ECG changes revealed evidence of inflammatory cardiac sequelae. All 30 athletes who underwent a mandatory CMR scan had normal findings. Athletes revealing de-novo ECG changes had a higher prevalence of cardiac symptoms (71% vs 12%, p<0.0001) and longer median symptom duration (5 days, IQR 3-10) compared with athletes without de-novo ECG changes (2 days, IQR 1-3, p<0.001). Among athletes without cardiac symptoms, the additional yield of de-novo ECG changes to detect cardiac inflammation was 20%. CONCLUSIONS: 3% of athletes demonstrated de-novo ECG changes post COVID-19 infection, of which 88% were diagnosed with cardiac inflammation. Most affected athletes exhibited cardiac symptoms; however, de-novo ECG changes contributed to a diagnosis of cardiac inflammation in 20% of athletes without cardiac symptoms.
Item Type: |
Article
|
Additional Information: |
© Author(s) (or their employer(s)) 2023.
Reuse of this manuscript version (excluding any databases, tables, diagrams, photographs and other images or illustrative material included where a another copyright owner is identified) is permitted strictly pursuant to the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC-BY-NC 4.0) http://creativecommons.org/licenses/by-nc/4.0/ |
Keywords: |
Cardiomyopathies, Electrocardiography, Myocarditis, Cardiomyopathies, Electrocardiography, Myocarditis, 1102 Cardiorespiratory Medicine and Haematology, 1103 Clinical Sciences, Cardiovascular System & Hematology |
SGUL Research Institute / Research Centre: |
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) |
Journal or Publication Title: |
Heart |
ISSN: |
1468-201X |
Language: |
eng |
Dates: |
Date | Event |
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6 May 2023 | Published | 27 March 2023 | Published Online | 21 February 2023 | Accepted |
|
Publisher License: |
Creative Commons: Attribution-Noncommercial 4.0 |
Projects: |
Project ID | Funder | Funder ID |
---|
UNSPECIFIED | Cardiac Risk in the Young | UNSPECIFIED | UNSPECIFIED | Conselho Nacional de Pesquisa, Brazilia, Brazil | UNSPECIFIED |
|
PubMed ID: |
37039240 |
![](http://static.pubmed.gov/portal/portal3rc.fcgi/2745237/img/27842) |
Go to PubMed abstract |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/115353 |
Publisher's version: |
https://doi.org/10.1136/heartjnl-2022-322211 |
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