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Lower Risk of Multisystem Inflammatory Syndrome in Children (MIS-C) with the Delta and Omicron variants of SARS-CoV-2.

Cohen, JM; Carter, MJ; Ronny Cheung, C; Ladhani, S; Evelina PIMS-TS Study Group (2023) Lower Risk of Multisystem Inflammatory Syndrome in Children (MIS-C) with the Delta and Omicron variants of SARS-CoV-2. Clin Infect Dis, 76 (3). e518-e521. ISSN 1537-6591 https://doi.org/10.1093/cid/ciac553
SGUL Authors: Ladhani, Shamez Nizarali

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Abstract

Little is known about the MIS-C risk with different SARS-CoV-2 variants. In Southeast England, MIS-C rates per confirmed SARS-CoV-2 infections in 0-16 years-olds were 56% lower (rate ratio, 0.34; 95%CI, 0.23-0.50) during pre-vaccine Delta, 66% lower (0.44; 0.28-0.69) during post-vaccine Delta and 95% lower (0.05; 0.02-0.10) during the Omicron period.

Item Type: Article
Additional Information: This is a pre-copyedited, author-produced version of an article accepted for publication in Clinical Infectious Diseases following peer review. The version of record Jonathan M Cohen, Michael J Carter, C Ronny Cheung, Shamez Ladhani, for the Evelina Paediatric Inflammatory Multisystem Syndrome Temporally related to SARS-CoV-2 (PIMS-TS) Study Group, Lower Risk of Multisystem Inflammatory Syndrome in Children With the Delta and Omicron Variants of Severe Acute Respiratory Syndrome Coronavirus 2, Clinical Infectious Diseases, Volume 76, Issue 3, 1 February 2023, Pages e518–e521 is available online at: https://doi.org/10.1093/cid/ciac553
Keywords: COVID-19, MIS-C, PIMS-TS, SARS-CoV-2, coronavirus, Evelina PIMS-TS Study Group, 06 Biological Sciences, 11 Medical and Health Sciences, Microbiology
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Clin Infect Dis
ISSN: 1537-6591
Language: eng
Dates:
DateEvent
1 February 2023Published
5 July 2022Published Online
30 June 2022Accepted
Publisher License: Publisher's own licence
Projects:
Project IDFunderFunder ID
UNSPECIFIEDNational Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
PubMed ID: 35788276
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/114689
Publisher's version: https://doi.org/10.1093/cid/ciac553

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