Yan, Y; Hu, Q
(2022)
Molecular Epidemiology of SARS-CoV-2 by Sequencing.
Methods Mol Biol, 2452.
pp. 19-32.
ISSN 1940-6029
https://doi.org/10.1007/978-1-0716-2111-0_2
SGUL Authors: Hu, Qinxue
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Abstract
Sequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains preliminary information on the phylodynamics and phylogeography of this new virus. A maximum clade credibility tree (MCCT) was constructed using available whole genome sequences of SARS-CoV-2 and highly similar whole genome sequences from bat SARS-like coronavirus, which are available in GenBank. In this chapter, we describe the molecular epidemiology of SARS-CoV-2 by sequencing the viral genomes from confirmed COVID-19 patients, utilizing methods such as target fragment amplification, sequencing, alignment, and maximum similarity mapping.
| Item Type: | Article | ||||||||||||
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| Additional Information: | The version of record of this chapter, first published in Methods in Molecular Biology, is available online at Publisher’s website: https://doi.org/10.1007/978-1-0716-2111-0_2 | ||||||||||||
| Keywords: | COVID-19, Genotype, Molecular epidemiology, SARS-CoV-2, Sequencing, COVID-19, Genome, Viral, Humans, Molecular Epidemiology, Phylogeny, SARS-CoV-2, Humans, Phylogeny, Genome, Viral, Molecular Epidemiology, COVID-19, SARS-CoV-2, 0601 Biochemistry and Cell Biology, Developmental Biology | ||||||||||||
| SGUL Research Institute / Research Centre: | Academic Structure > Infection and Immunity Research Institute (INII) | ||||||||||||
| Journal or Publication Title: | Methods Mol Biol | ||||||||||||
| ISSN: | 1940-6029 | ||||||||||||
| Language: | eng | ||||||||||||
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| Publisher License: | Publisher's own licence | ||||||||||||
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| PubMed ID: | 35554898 | ||||||||||||
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| URI: | https://openaccess.sgul.ac.uk/id/eprint/114388 | ||||||||||||
| Publisher's version: | https://doi.org/10.1007/978-1-0716-2111-0_2 |
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