SORA

Advancing, promoting and sharing knowledge of health through excellence in teaching, clinical practice and research into the prevention and treatment of illness

Acute, Severe Traumatic Spinal Cord Injury: Monitoring from the Injury Site and Expansion Duraplasty.

Saadoun, S; Papadopoulos, MC (2021) Acute, Severe Traumatic Spinal Cord Injury: Monitoring from the Injury Site and Expansion Duraplasty. Neurosurg Clin N Am, 32 (3). pp. 365-376. ISSN 1558-1349 https://doi.org/10.1016/j.nec.2021.03.008
SGUL Authors: Papadopoulos, Marios Saadoun, Samira

[img]
Preview
PDF Accepted Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (1MB) | Preview

Abstract

We discuss 2 evolving management options for acute spinal cord injury that hold promise to further improve outcome: pressure monitoring from the injured cord and expansion duraplasty. Probes surgically implanted at the injury site can transduce intraspinal pressure, spinal cord perfusion pressure, and cord metabolism. Intraspinal pressure is not adequately reduced by bony decompression alone because the swollen, injured cord is compressed against the dura. Expansion duraplasty may be necessary to effectively decompress the injured cord. A randomized controlled trial called DISCUS is investigating expansion duraplasty as a novel treatment for acute, severe traumatic cervical spinal cord injury.

Item Type: Article
Additional Information: © 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Blood pressure, Critical care, Decompression, Duraplasty, Intraspinal pressure, Microdialysis, Spinal cord injury, Spinal cord perfusion pressure, Blood pressure, Critical care, Decompression, Duraplasty, Intraspinal pressure, Microdialysis, Spinal cord injury, Spinal cord perfusion pressure, Neurology & Neurosurgery
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Neurosurg Clin N Am
ISSN: 1558-1349
Language: eng
Dates:
DateEvent
July 2021Published
7 May 2021Published Online
1 May 2021Accepted
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Projects:
Project IDFunderFunder ID
NIHR130048National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
PubMed ID: 34053724
Web of Science ID: WOS:000655660300009
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/113349
Publisher's version: https://doi.org/10.1016/j.nec.2021.03.008

Actions (login required)

Edit Item Edit Item