Saadoun, S; Papadopoulos, MC
(2021)
Acute, Severe Traumatic Spinal Cord Injury: Monitoring from the Injury Site and Expansion Duraplasty.
Neurosurg Clin N Am, 32 (3).
pp. 365-376.
ISSN 1558-1349
https://doi.org/10.1016/j.nec.2021.03.008
SGUL Authors: Papadopoulos, Marios Saadoun, Samira
Abstract
We discuss 2 evolving management options for acute spinal cord injury that hold promise to further improve outcome: pressure monitoring from the injured cord and expansion duraplasty. Probes surgically implanted at the injury site can transduce intraspinal pressure, spinal cord perfusion pressure, and cord metabolism. Intraspinal pressure is not adequately reduced by bony decompression alone because the swollen, injured cord is compressed against the dura. Expansion duraplasty may be necessary to effectively decompress the injured cord. A randomized controlled trial called DISCUS is investigating expansion duraplasty as a novel treatment for acute, severe traumatic cervical spinal cord injury.
Item Type: |
Article
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Additional Information: |
© 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Keywords: |
Blood pressure, Critical care, Decompression, Duraplasty, Intraspinal pressure, Microdialysis, Spinal cord injury, Spinal cord perfusion pressure, Blood pressure, Critical care, Decompression, Duraplasty, Intraspinal pressure, Microdialysis, Spinal cord injury, Spinal cord perfusion pressure, Neurology & Neurosurgery |
SGUL Research Institute / Research Centre: |
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) |
Journal or Publication Title: |
Neurosurg Clin N Am |
ISSN: |
1558-1349 |
Language: |
eng |
Dates: |
Date | Event |
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July 2021 | Published | 7 May 2021 | Published Online | 1 May 2021 | Accepted |
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Publisher License: |
Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0 |
Projects: |
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PubMed ID: |
34053724 |
Web of Science ID: |
WOS:000655660300009 |
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Go to PubMed abstract |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/113349 |
Publisher's version: |
https://doi.org/10.1016/j.nec.2021.03.008 |
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