Pitt, MJ; Morris, JK
(2021)
European trends in mortality in children with congenital anomalies: 2000–2015.
Birth Defects Research, 113 (12).
pp. 958-967.
ISSN 2472-1727
https://doi.org/10.1002/bdr2.1892
SGUL Authors: Morris, Joan Katherine
Abstract
Objective
To investigate if the survival of children with congenital anomalies has improved from 2000 to 2015 and whether there is heterogeneity in the improvements across Europe.
Design
Population‐based study of routine collected data from the WHO database on mortality and causes.
Setting
Data on 31 European countries from 2000 to 2015.
Main outcome measures
All‐cause and congenital anomaly mortality rates for infants and children up to age 9 in countries and regions of Europe.
Results
The relative odds of all‐cause mortality in 2015 compared with 2000 was 0.54 (95% CI: 0.50–0.59) for under 1, 0.48 (95% CI: 0.44–0.53) for ages 1–4, and 0.53 (95% CI: 0.49–0.56) for ages 5–9 with the relative odds of mortality from congenital anomalies being 0.49 (95% CI: 0.44–0.55), 0.51 (95% CI: 0.44–0.60), and 0.65 (95% CI: 0.53–0.80), respectively. The proportion of deaths from congenital anomalies remained relatively constant over time (26, 16, and 9% for under 1, ages 1–4, and ages 5–9, respectively) and was similar in all regions of Europe. For mortality from all causes and from congenital anomalies heterogeneity between countries and regions of Europe was high, with the countries in Eastern Europe having higher rates, but also experiencing greater relative reductions in mortality from 2000 to 2015.
Conclusion
There was a large geo‐spatial disparity in all cause and congenital anomaly mortality for infants and children up to 9. However, all regions saw a significant decrease in all cause and congenital anomaly mortality rates, with the proportions of deaths from congenital anomalies remaining constant over this time.
Item Type: |
Article
|
Additional Information: |
© 2021 The Authors. Birth Defects Research published by Wiley Periodicals LLC.
This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
SGUL Research Institute / Research Centre: |
Academic Structure > Population Health Research Institute (INPH) |
Journal or Publication Title: |
Birth Defects Research |
ISSN: |
2472-1727 |
Language: |
en |
Dates: |
Date | Event |
---|
15 July 2021 | Published | 25 March 2021 | Published Online | 14 February 2021 | Accepted |
|
Publisher License: |
Creative Commons: Attribution 4.0 |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/113084 |
Publisher's version: |
https://doi.org/10.1002/bdr2.1892 |
Statistics
Item downloaded times since 26 Mar 2021.
Actions (login required)
![Edit Item](/style/images/action_view.png) |
Edit Item |