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Vaccine Effectiveness against DS-1-Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013-2015.

Jere, KC; Bar-Zeev, N; Chande, A; Bennett, A; Pollock, L; Sanchez-Lopez, PF; Nakagomi, O; Tate, JE; Parashar, UD; Heyderman, RS; et al. Jere, KC; Bar-Zeev, N; Chande, A; Bennett, A; Pollock, L; Sanchez-Lopez, PF; Nakagomi, O; Tate, JE; Parashar, UD; Heyderman, RS; French, N; Iturriza-Gomara, M; Cunliffe, NA (2019) Vaccine Effectiveness against DS-1-Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013-2015. Emerg Infect Dis, 25 (9). pp. 1734-1737. ISSN 1080-6059 https://doi.org/10.3201/eid2509.190258
SGUL Authors: Bennett, Aisleen

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Abstract

Atypical DS-1-like G1P[8] rotaviruses emerged in 2013 in Malawi after rotavirus vaccine introduction. Vaccine effectiveness among infants hospitalized with acute DS-1-like G1P[8] rotavirus gastroenteritis was 85.6% (95% CI 34.4%-96.8%). These findings suggest that vaccine provides protection against these strains despite their emergence coinciding with vaccine introduction.

Item Type: Article
Additional Information: Jere KC, Bar-Zeev N, Chande A, Bennett A, Pollock L, Sanchez-Lopez PF, et al. Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015. Emerg Infect Dis. 2019;25(9):1734-1737. https://dx.doi.org/10.3201/eid2509.190258
Keywords: Malawi, genome constellation, genotyping, infants, rotavirus, vaccine effectiveness, vaccines, viruses, whole-genome sequencing, Child, Hospitalized, Child, Preschool, Female, Gastroenteritis, Humans, Infant, Infant, Newborn, Malawi, Male, Rotavirus, Rotavirus Infections, Rotavirus Vaccines, Vaccines, Attenuated, Humans, Rotavirus, Rotavirus Infections, Gastroenteritis, Vaccines, Attenuated, Rotavirus Vaccines, Child, Preschool, Infant, Infant, Newborn, Child, Hospitalized, Malawi, Female, Male, Microbiology, 1108 Medical Microbiology, 1117 Public Health and Health Services, 1103 Clinical Sciences
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Emerg Infect Dis
ISSN: 1080-6059
Language: eng
Publisher License: Publisher's own licence
Projects:
Project IDFunderFunder ID
091909/Z/10/ZWellcome Trusthttp://dx.doi.org/10.13039/100004440
201945/Z/16/ZWellcome Trusthttp://dx.doi.org/10.13039/100004440
PubMed ID: 31441761
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/112887
Publisher's version: https://doi.org/10.3201/eid2509.190258

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