Mailli, L; Auyoung, EY; Angileri, SA; Ameli-Renani, S; Ratnam, L; Das, R; Chun, J-Y; Das, S; Manyonda, I; Belli, A-M
(2020)
Predicting the Fibroid-Migratory Impact of UAE: Role of Pre-embolization MRI Characteristics.
Cardiovasc Intervent Radiol, 43 (3).
pp. 453-458.
ISSN 1432-086X
https://doi.org/10.1007/s00270-019-02348-w
SGUL Authors: Manyonda, Isaac Tainzana
Abstract
AIM: To investigate potential factors on MR imaging that could be used to predict migration of uterine fibroids post-UAE. METHODS AND MATERIALS: We retrospectively reviewed patients referred for UAE having pre-procedural and 6 months post-procedural MRI, at a tertiary centre, over a 1-year period. Pre- and post-UAE images were reviewed in 64 women by two radiologists to identify the sub-type, dimensions, and infarction rate of each dominant fibroid. The shortest distance between the fibroid and the endometrial wall was measured to determine intramural fibroid movement. Paired sample T tests and two-sample T tests were used to compare between pre- and post-embolization variations and between migrated and non-migrated intramural fibroids, respectively. After preliminary results suggested potential predictors of intramural fibroids migration, we tested our findings against the non-dominant intramural fibroids in the same patients. RESULTS: Review of images revealed 35 dominant intramural fibroids, of which eight migrated to become submucosal fibroids, while five were either partially or completely expelled. These 13 migrated fibroids had a shorter pre-procedural minimum endometrial distance (range 1-2.4 mm) and greater maximum fibroid diameter (range 5.1-18.1 cm), when compared to non-migrating fibroids. On image reassessment, the migrated non-dominant intramural fibroids had a minimum endometrial distance and maximum fibroid diameter within the same range. CONCLUSION: Intramural fibroids with a minimum endometrial distance less than 2.4 mm and a maximum fibroid diameter greater than 5.1 cm have a high likelihood of migrating towards the endometrial cavity after UAE.
Item Type: |
Article
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Additional Information: |
© The Author(s) 2019
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
Keywords: |
Fibroid MRI, Fibroids, Gynaecologic interventions, Uterine artery embolisation, Uterine fibroid embolisation, Adult, Female, Humans, Leiomyoma, Magnetic Resonance Imaging, Middle Aged, Retrospective Studies, Treatment Outcome, Uterine Artery Embolization, Uterine Neoplasms, Uterus, Uterus, Humans, Leiomyoma, Uterine Neoplasms, Magnetic Resonance Imaging, Treatment Outcome, Retrospective Studies, Adult, Middle Aged, Female, Uterine Artery Embolization, Fibroids, Uterine fibroid embolisation, Uterine artery embolisation, Gynaecologic interventions, Fibroid MRI, 1102 Cardiorespiratory Medicine and Haematology, Nuclear Medicine & Medical Imaging |
SGUL Research Institute / Research Centre: |
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) |
Journal or Publication Title: |
Cardiovasc Intervent Radiol |
ISSN: |
1432-086X |
Language: |
eng |
Dates: |
Date | Event |
---|
March 2020 | Published | 24 October 2019 | Published Online | 30 September 2019 | Accepted |
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Publisher License: |
Creative Commons: Attribution 4.0 |
PubMed ID: |
31650245 |
Web of Science ID: |
WOS:000492364600004 |
![](http://static.pubmed.gov/portal/portal3rc.fcgi/2745237/img/27842) |
Go to PubMed abstract |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/112730 |
Publisher's version: |
https://doi.org/10.1007/s00270-019-02348-w |
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