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Modulating the gut-liver axis and the pivotal role of the faecal microbiome in cirrhosis.

Woodhouse, C; Singanayagam, A; Patel, VC (2020) Modulating the gut-liver axis and the pivotal role of the faecal microbiome in cirrhosis. Clin Med (Lond), 20 (5). pp. 493-500. ISSN 1473-4893 https://doi.org/10.7861/clinmed.2020-0676
SGUL Authors: Singanayagam, Arjuna

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Abstract

Cirrhosis is associated with intestinal dysbiosis, with specific alterations in the gut microbiota linked to particular aetiologies and manifestations of the disease. We review the role of the gut microbiome and the importance of the intestinal barrier in cirrhosis, provide an overview of the terminology and techniques relevant to this emerging area, and discuss the latest developments in therapies targeting the gut-liver axis.

Item Type: Article
Additional Information: © Royal College of Physicians 2020. All rights reserved.
Keywords: Microbiota, cirrhosis, dysbiosis, faecal microbial transplantation, gut–liver axis, 1103 Clinical Sciences, General Clinical Medicine
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Clin Med (Lond)
ISSN: 1473-4893
Language: eng
Dates:
DateEvent
15 September 2020Published Online
1 September 2020Published
13 August 2020Accepted
Publisher License: Publisher's own licence
PubMed ID: 32934044
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/112412
Publisher's version: https://doi.org/10.7861/clinmed.2020-0676

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