Finocchiaro, G;
Merlo, M;
Sheikh, N;
De Angelis, G;
Papadakis, M;
Olivotto, I;
Rapezzi, C;
Carr-White, G;
Sharma, S;
Mestroni, L;
et al.
Finocchiaro, G; Merlo, M; Sheikh, N; De Angelis, G; Papadakis, M; Olivotto, I; Rapezzi, C; Carr-White, G; Sharma, S; Mestroni, L; Sinagra, G
(2020)
The electrocardiogram in the diagnosis and management of patients with dilated cardiomyopathy.
Eur J Heart Fail, 22 (7).
pp. 1097-1107.
ISSN 1879-0844
https://doi.org/10.1002/ejhf.1815
SGUL Authors: Sharma, Sanjay
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Abstract
The term dilated cardiomyopathy (DCM) defines a heterogeneous group of cardiac disorders, which are characterized by left ventricular or biventricular dilatation and systolic dysfunction in the absence of abnormal loading conditions or coronary artery disease sufficient to cause global systolic impairment. In approximately one third of cases, DCM is familial with a genetic pathogenesis and various patterns of inheritance. Although the electrocardiogram (ECG) has been considered traditionally non-specific in DCM, the recently acquired knowledge of the genotype-phenotype correlations provides novel opportunities to identify patterns and abnormalities that may point toward specific DCM subtypes. A learned ECG interpretation in combination with an appropriate use of other ECG-based techniques including ambulatory ECG monitoring, exercise tolerance test and imaging modalities, such as echocardiography and cardiovascular magnetic resonance, may allow the early identification of specific genetic or acquired forms of DCM. Furthermore, ECG abnormalities may reflect the severity of the disease and provide a useful tool in risk stratification and management. In the present review, we discuss the current role of the ECG in the diagnosis and management of DCM. We describe various clinical settings where the appropriate use and interpretation of the ECG can provide invaluable clues, contributing to the important role of this basic tool as cardiovascular medicine evolves.
Item Type: | Article | |||||||||||||||
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Additional Information: | © 2020 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. | |||||||||||||||
Keywords: | Diagnosis, Dilated cardiomyopathy, Electrocardiogram, Management, 1102 Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology | |||||||||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) | |||||||||||||||
Journal or Publication Title: | Eur J Heart Fail | |||||||||||||||
ISSN: | 1879-0844 | |||||||||||||||
Language: | eng | |||||||||||||||
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Publisher License: | Creative Commons: Attribution-Noncommercial 4.0 | |||||||||||||||
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PubMed ID: | 32243666 | |||||||||||||||
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URI: | https://openaccess.sgul.ac.uk/id/eprint/111838 | |||||||||||||||
Publisher's version: | https://doi.org/10.1002/ejhf.1815 |
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