Kirwan, DE;
Ugarte-Gil, C;
Gilman, RH;
Caviedes, L;
Rizvi, H;
Ticona, E;
Chavez, G;
Cabrera, JL;
Matos, ED;
Evans, CA;
et al.
Kirwan, DE; Ugarte-Gil, C; Gilman, RH; Caviedes, L; Rizvi, H; Ticona, E; Chavez, G; Cabrera, JL; Matos, ED; Evans, CA; Moore, DAJ; Friedland, JS; Lymph Node TB Working Group, Peru
(2016)
Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance.
J Clin Microbiol, 54 (1).
pp. 185-189.
ISSN 1098-660X
https://doi.org/10.1128/JCM.02227-15
SGUL Authors: Friedland, Jonathan Samuel
Abstract
In this study, 132 patients with lymphadenopathy were investigated. Fifty-two (39.4%) were diagnosed with tuberculosis (TB). The microscopic observation drug susceptibility (MODS) assay provided rapid (13 days), accurate diagnosis (sensitivity, 65.4%) and reliable drug susceptibility testing (DST). Despite its lower sensitivity than that of other methods, its faster results and simultaneous DST are advantageous in resource-poor settings, supporting the incorporation of MODS into diagnostic algorithms for extrapulmonary TB.
| Item Type: |
Article
|
| Additional Information: |
Copyright © 2015 Kirwan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/). |
| Keywords: |
Adolescent, Adult, Aged, Aged, 80 and over, Bacteriological Techniques, Female, Humans, Male, Microscopy, Middle Aged, Sensitivity and Specificity, Time Factors, Tuberculosis, Lymph Node, Tuberculosis, Multidrug-Resistant, Young Adult, Lymph Node TB Working Group, Peru, Humans, Tuberculosis, Lymph Node, Tuberculosis, Multidrug-Resistant, Microscopy, Bacteriological Techniques, Sensitivity and Specificity, Time Factors, Adolescent, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male, Young Adult, 06 Biological Sciences, 07 Agricultural And Veterinary Sciences, 11 Medical And Health Sciences, Microbiology |
| Journal or Publication Title: |
J Clin Microbiol |
| ISSN: |
1098-660X |
| Language: |
eng |
| Dates: |
| Date | Event |
|---|
| January 2016 | Published | | 30 December 2015 | Published Online | | 12 September 2015 | Accepted |
|
| Publisher License: |
Creative Commons: Attribution 3.0 |
| Projects: |
|
| PubMed ID: |
26511739 |
| Web of Science ID: |
WOS:000367537600033 |
 |
Go to PubMed abstract |
| URI: |
https://openaccess.sgul.ac.uk/id/eprint/110639 |
| Publisher's version: |
https://doi.org/10.1128/JCM.02227-15 |
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