Rudnicka, AR; Kapetanakis, VV; Wathern, AK; Logan, NS; Gilmartin, B; Whincup, PH; Cook, DG; Owen, CG
(2016)
Global variations and time trends in the prevalence of childhood myopia, a systematic review and quantitative meta-analysis: implications for aetiology and early prevention.
Br J Ophthalmol, 100 (7).
pp. 882-890.
ISSN 1468-2079
https://doi.org/10.1136/bjophthalmol-2015-307724
SGUL Authors: Cook, Derek Gordon Owen, Christopher Grant Rudnicka, Alicja Regina Whincup, Peter Hynes
Abstract
The aim of this review was to quantify the global variation in childhood myopia prevalence over time taking account of demographic and study design factors. A systematic review identified population-based surveys with estimates of childhood myopia prevalence published by February 2015. Multilevel binomial logistic regression of log odds of myopia was used to examine the association with age, gender, urban versus rural setting and survey year, among populations of different ethnic origins, adjusting for study design factors. 143 published articles (42 countries, 374 349 subjects aged 1-18 years, 74 847 myopia cases) were included. Increase in myopia prevalence with age varied by ethnicity. East Asians showed the highest prevalence, reaching 69% (95% credible intervals (CrI) 61% to 77%) at 15 years of age (86% among Singaporean-Chinese). Blacks in Africa had the lowest prevalence; 5.5% at 15 years (95% CrI 3% to 9%). Time trends in myopia prevalence over the last decade were small in whites, increased by 23% in East Asians, with a weaker increase among South Asians. Children from urban environments have 2.6 times the odds of myopia compared with those from rural environments. In whites and East Asians sex differences emerge at about 9 years of age; by late adolescence girls are twice as likely as boys to be myopic. Marked ethnic differences in age-specific prevalence of myopia exist. Rapid increases in myopia prevalence over time, particularly in East Asians, combined with a universally higher risk of myopia in urban settings, suggest that environmental factors play an important role in myopia development, which may offer scope for prevention.
Item Type: |
Article
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Additional Information: |
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Keywords: |
Child health (paediatrics), Epidemiology, Optics and Refraction, Public health, Child, Ethnic Groups, Female, Global Health, Humans, Male, Myopia, Prevalence, Rural Population, Surveys and Questionnaires, Time Factors, Ophthalmology & Optometry, 1103 Clinical Sciences, 1113 Ophthalmology And Optometry, 1117 Public Health And Health Services |
SGUL Research Institute / Research Centre: |
Academic Structure > Population Health Research Institute (INPH) |
Journal or Publication Title: |
Br J Ophthalmol |
ISSN: |
1468-2079 |
Language: |
eng |
Dates: |
Date | Event |
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July 2016 | Published | 22 January 2016 | Published Online | 2 January 2016 | Accepted |
|
Publisher License: |
Creative Commons: Attribution-Noncommercial 4.0 |
Projects: |
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PubMed ID: |
26802174 |
Web of Science ID: |
WOS:000380747000003 |
![](http://static.pubmed.gov/portal/portal3rc.fcgi/2745237/img/27842) |
Go to PubMed abstract |
URI: |
https://openaccess.sgul.ac.uk/id/eprint/109982 |
Publisher's version: |
https://doi.org/10.1136/bjophthalmol-2015-307724 |
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