Jackson, C;
Southern, J;
Lalvani, A;
Drobniewski, F;
Griffiths, CJ;
Lipman, M;
Bothamley, GH;
Deeks, JJ;
Imran, A;
Kon, OM;
et al.
Jackson, C; Southern, J; Lalvani, A; Drobniewski, F; Griffiths, CJ; Lipman, M; Bothamley, GH; Deeks, JJ; Imran, A; Kon, OM; Mpofu, S; Nikolayevskyy, V; Rees-Roberts, M; Sitch, A; Sridhar, S; Tsou, C-Y; Whitworth, H; Abubakar, I
(2019)
Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.
Thorax, 74 (1).
pp. 91-94.
ISSN 0040-6376
https://doi.org/10.1136/thoraxjnl-2017-211124
SGUL Authors: Jackson, Charlotte Rebecca
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Abstract
We conducted a cross-sectional analysis of baseline data from a UK cohort study which enrolled participants at risk of latent tuberculosis infection (LTBI, defined as a positive result for either of the two interferon gamma release assays). Binomial regression with a log link was used to estimate crude and adjusted prevalence ratios (PRs) and 95% CIs for the relationship between diabetes mellitus (DM) and LTBI. Adjusted for age, sex, ethnicity, body mass index and the presence of other immunocompromising conditions, DM was associated with a 15% higher prevalence of LTBI (adjusted PR=1.15, 95% CI 1.02 to 1.30, p=0.025).
Item Type: | Article | ||||||||||||
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Additional Information: | This article has been accepted for publication in Thorax following peer review. The definitive copyedited, typeset version Jackson C, Southern J, Lalvani A, et al Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort Thorax 2019;74:91-94 is available online at: http://dx.doi.org/10.1136/thoraxjnl-2017-211124 | ||||||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Infection and Immunity Research Institute (INII) | ||||||||||||
Journal or Publication Title: | Thorax | ||||||||||||
ISSN: | 0040-6376 | ||||||||||||
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Publisher License: | Publisher's own licence | ||||||||||||
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URI: | https://openaccess.sgul.ac.uk/id/eprint/109823 | ||||||||||||
Publisher's version: | https://doi.org/10.1136/thoraxjnl-2017-211124 |
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