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Analysis of aortic area/height ratio in patients with thoracic aortic aneurysm and Type A dissection.

Acharya, MN; Youssefi, P; Soppa, G; Valencia, O; Nowell, J; Kanagasabay, R; Edsell, M; Morgan, R; Tome, M; Jahangiri, M (2018) Analysis of aortic area/height ratio in patients with thoracic aortic aneurysm and Type A dissection. Eur J Cardiothorac Surg, 54 (4). pp. 696-701. ISSN 1873-734X https://doi.org/10.1093/ejcts/ezy110
SGUL Authors: Jahangiri, Marjan Tome, Maria Teresa

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Abstract

OBJECTIVES: Significant proportions of aortic dissections occur at aortic diameters <5.5 cm. By indexing aortic area to height and correlating with absolute aortic diameter, we sought to identify those aneurysm patients with aortic diameters <5.5 cm who do not meet current size thresholds for surgery, yet with corresponding abnormal indexed aortic areas (IAAs) >10 cm2/m, are at increased risk of aortic complications. METHODS: IAAs were calculated at 3 aortic locations in 187 aneurysm and 66 dissection patients operated on between 2010 and 2016 at our tertiary aortic centre. Proportions of patients with IAA >10 cm2/m, mean IAAs corresponding to aortic diameters <4.0 cm, 4.0-4.5 cm, 4.5-5.0 cm, 5.0-5.5 cm and >5.5 cm, and mean aortic diameters corresponding to IAAs 10-12 cm2/m, 12-14 cm2/m and >14 cm2/m were determined. RESULTS: Proportions of patients with abnormal IAAs were similar in both groups. In all, 49.1% of aneurysm patients with aortic diameters 4.5-5.0 cm, and 98.5% with aortic diameters 5.0-5.5 cm had abnormal IAAs. Out of 207 separate aneurysms with IAAs >10 cm2/m between the mid-sinus and mid-ascending aorta, only 139 (69.5%) would warrant surgery according to existing guidelines. CONCLUSIONS: Using the IAA, we identified a significant proportion of patients with thoracic aortic aneurysms who are at increased risk of aortic complications, despite current aortic guidelines not endorsing surgical intervention in this group. Our data suggests the IAA may be useful in preoperative risk evaluation and as a criterion for surgery.

Item Type: Article
Additional Information: Correction available at http://openaccess.sgul.ac.uk/110126/ or via the publisher's website at https://doi.org/10.1093/ejcts/ezy282 This is a pre-copyedited, author-produced version of an article accepted for publication in European Journal of Cardio-Thoracic Surgery following peer review. The version of record Metesh Nalin Acharya, Pouya Youssefi, Gopal Soppa, Oswaldo Valencia, Justin Nowell, Robin Kanagasabay, Mark Edsell, Robert Morgan, Maite Tome, Marjan Jahangiri; Analysis of aortic area/height ratio in patients with thoracic aortic aneurysm and Type A dissection, European Journal of Cardio-Thoracic Surgery, Volume 54, Issue 4, 1 October 2018, Pages 696–701 is available online at: https://doi.org/10.1093/ejcts/ezy110
Keywords: 1102 Cardiovascular Medicine And Haematology
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Eur J Cardiothorac Surg
ISSN: 1873-734X
Language: eng
Dates:
DateEvent
October 2018Published
15 March 2018Published Online
17 February 2018Accepted
Publisher License: Publisher's own licence
PubMed ID: 29554275
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/109803
Publisher's version: https://doi.org/10.1093/ejcts/ezy110

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