Bright, PD; Lupiya, D; van Oosterhout, JJ; Chen, A; Harrison, TS; Chan, AK
(2018)
The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options.
MEDICAL MYCOLOGY CASE REPORTS, 19.
pp. 9-12.
ISSN 2211-7539
https://doi.org/10.1016/j.mmcr.2017.10.002
SGUL Authors: Harrison, Thomas Stephen
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Abstract
This case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation. The patient had well-controlled HIV (CD4 count over 200 cells/mL). The immunosuppressive effects of the pregnancy likely contributed to the development of cryptococcal disease. The patient was successfully treated with two weeks of amphotericin B followed by fluconazole, delivered a healthy baby, but remained with a permanent severe neurological deficit.
| Item Type: | Article |
|---|---|
| Additional Information: | © 2017 The Authors. Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/). |
| Keywords: | Cryptococcal meningitis, Pregnancy, Treatment, HIV, Malawi |
| SGUL Research Institute / Research Centre: | Academic Structure > Infection and Immunity Research Institute (INII) |
| Journal or Publication Title: | MEDICAL MYCOLOGY CASE REPORTS |
| ISSN: | 2211-7539 |
| Publisher License: | Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0 |
| Web of Science ID: | WOS:000422685800003 |
| URI: | https://openaccess.sgul.ac.uk/id/eprint/109583 |
| Publisher's version: | https://doi.org/10.1016/j.mmcr.2017.10.002 |
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