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Type 2 myocardial infarction: the chimaera of cardiology?

Collinson, P; Lindahl, B (2015) Type 2 myocardial infarction: the chimaera of cardiology? Heart, 101 (21). pp. 1697-1703. ISSN 1468-201X https://doi.org/10.1136/heartjnl-2014-307122
SGUL Authors: Collinson, Paul

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Abstract

The term type 2 myocardial infarction first appeared as part of the universal definition of myocardial infarction. It was introduced to cover a group of patients who had elevation of cardiac troponin but did not meet the traditional criteria for acute myocardial infarction although they were considered to have an underlying ischaemic aetiology for the myocardial damage observed. Since first inception, the term type 2 myocardial infarction has always been vague. Although attempts have been made to produce a systematic definition of what constitutes a type 2 myocardial infarction, it has been more often characterised by what it is not rather than what it is. Clinical studies that have used type 2 myocardial infarction as a diagnostic criterion have produced disparate incidence figures. The range of associated clinical conditions differs from study to study. Additionally, there are no agreed or evidence-based treatment strategies for type 2 myocardial infarction. The authors believe that the term type 2 myocardial infarction is confusing and not evidence-based. They consider that there is good reason to stop using this term and consider instead the concept of secondary myocardial injury that relates to the underlying pathophysiology of the primary clinical condition.

Item Type: Article
Additional Information: This article has been accepted for publication in Heart, 2015 following peer review, and the Version of Record can be accessed online at http://dx.doi.org/10.1136/heartjnl-2014-307122.
Keywords: Biomarkers, Diagnosis, Differential, Dissent and Disputes, Humans, Myocardial Infarction, Myocardial Ischemia, Prognosis, Terminology as Topic, Troponin, Humans, Myocardial Ischemia, Myocardial Infarction, Troponin, Diagnosis, Differential, Prognosis, Dissent and Disputes, Terminology as Topic, Biomarkers, Cardiovascular System & Hematology, 1102 Cardiovascular Medicine And Haematology
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) > Cardiac (INCCCA)
Journal or Publication Title: Heart
ISSN: 1468-201X
Language: eng
Dates:
DateEvent
11 October 2015Published
28 July 2015Published Online
6 July 2015Accepted
Publisher License: Publisher's own licence
PubMed ID: 26220812
Web of Science ID: WOS:000362725400005
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/108965
Publisher's version: https://doi.org/10.1136/heartjnl-2014-307122

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