Dell'Osso, B;
Benatti, B;
Hollander, E;
Fineberg, N;
Stein, DJ;
Lochner, C;
Nicolini, H;
Lanzagorta, N;
Palazzo, C;
Altamura, AC;
et al.
Dell'Osso, B; Benatti, B; Hollander, E; Fineberg, N; Stein, DJ; Lochner, C; Nicolini, H; Lanzagorta, N; Palazzo, C; Altamura, AC; Marazziti, D; Pallanti, S; Van Ameringen, M; Karamustafalioglu, O; Drummond, LM; Hranov, L; Figee, M; Grant, JE; Zohar, J; Denys, D; Menchon, JM
(2016)
Childhood, adolescent and adult age at onset and related clinical correlates in obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS).
International Journal of Psychiatry in Clinical Practice, 20 (4).
pp. 210-217.
ISSN 1365-1501
https://doi.org/10.1080/13651501.2016.1207087
SGUL Authors: Drummond, Lynne Marjorie
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Abstract
OBJECTIVE: Many studies suggest that age at onset (AAO) is an important factor for clinically differentiating patients with juvenile and adult onset of obsessive-compulsive disorder (OCD). The present international study aimed to assess the prevalence of different AAO groups and compare related socio-demographic and clinical features in a large sample of OCD patients. METHODS: A total of 431 OCD outpatients, participating in the ICOCS network, were first categorised in groups with childhood (≤12 years), adolescent (13-17 years) and adult-onset (≥18 years), then in pre-adult and adult onset (≥18 years) and their socio-demographic and clinical features compared. RESULTS: Twenty-one percent (n = 92) of the sample reported childhood onset, 36% (n = 155) adolescent onset, and 43% (n = 184) adult onset. Patients with adult onset showed a significantly higher proportion of females compared with the other subgroups (χ(2 )=( )10.9, p< 0.05). Childhood- and adolescent-onset patients had been more frequently treated with cognitive behavioural therapy (CBT), compared to adult-onset patients (χ(2 )=( )11.5; p < 0.05). The pre-adult- versus adult-onset analysis did not show any additional significant difference. CONCLUSIONS: The present international multicentre study confirms that OCD onset occurs more frequently before adult age, with approximately one out of five patients showing childhood onset. Pre-adult onset was associated with higher rate of CBT, while adult onset was more prevalent in females.
Item Type: | Article | ||||||||
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Additional Information: | Copyright 2016 Taylor and Francis. This is an Accepted Manuscript of an article published by Taylor & Francis in International Journal of Psychiatry in Clinical Practice on 19 July 2016, available online: http://dx.doi.org/10.1080/13651501.2016.1207087 | ||||||||
Keywords: | Age at onset, cognitive behavioural therapy, gender, obsessive–compulsive disorder, Age at onset, cognitive behavioural therapy, gender, obsessive-compulsive disorder, Age at onset, cognitive behavioural therapy, gender, obsessive–compulsive disorder, Psychiatry, 1103 Clinical Sciences, 1701 Psychology | ||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Institute of Medical & Biomedical Education (IMBE) Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE ) |
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Journal or Publication Title: | International Journal of Psychiatry in Clinical Practice | ||||||||
ISSN: | 1365-1501 | ||||||||
Language: | eng | ||||||||
Dates: |
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PubMed ID: | 27433835 | ||||||||
Web of Science ID: | WOS:000384532400002 | ||||||||
Go to PubMed abstract | |||||||||
URI: | https://openaccess.sgul.ac.uk/id/eprint/108474 | ||||||||
Publisher's version: | https://doi.org/10.1080/13651501.2016.1207087 |
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