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Childhood, adolescent and adult age at onset and related clinical correlates in obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS).

Dell'Osso, B; Benatti, B; Hollander, E; Fineberg, N; Stein, DJ; Lochner, C; Nicolini, H; Lanzagorta, N; Palazzo, C; Altamura, AC; et al. Dell'Osso, B; Benatti, B; Hollander, E; Fineberg, N; Stein, DJ; Lochner, C; Nicolini, H; Lanzagorta, N; Palazzo, C; Altamura, AC; Marazziti, D; Pallanti, S; Van Ameringen, M; Karamustafalioglu, O; Drummond, LM; Hranov, L; Figee, M; Grant, JE; Zohar, J; Denys, D; Menchon, JM (2016) Childhood, adolescent and adult age at onset and related clinical correlates in obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). International Journal of Psychiatry in Clinical Practice, 20 (4). pp. 210-217. ISSN 1365-1501 https://doi.org/10.1080/13651501.2016.1207087
SGUL Authors: Drummond, Lynne Marjorie

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Abstract

OBJECTIVE: Many studies suggest that age at onset (AAO) is an important factor for clinically differentiating patients with juvenile and adult onset of obsessive-compulsive disorder (OCD). The present international study aimed to assess the prevalence of different AAO groups and compare related socio-demographic and clinical features in a large sample of OCD patients. METHODS: A total of 431 OCD outpatients, participating in the ICOCS network, were first categorised in groups with childhood (≤12 years), adolescent (13-17 years) and adult-onset (≥18 years), then in pre-adult and adult onset (≥18 years) and their socio-demographic and clinical features compared. RESULTS: Twenty-one percent (n = 92) of the sample reported childhood onset, 36% (n = 155) adolescent onset, and 43% (n = 184) adult onset. Patients with adult onset showed a significantly higher proportion of females compared with the other subgroups (χ(2 )=( )10.9, p< 0.05). Childhood- and adolescent-onset patients had been more frequently treated with cognitive behavioural therapy (CBT), compared to adult-onset patients (χ(2 )=( )11.5; p < 0.05). The pre-adult- versus adult-onset analysis did not show any additional significant difference. CONCLUSIONS: The present international multicentre study confirms that OCD onset occurs more frequently before adult age, with approximately one out of five patients showing childhood onset. Pre-adult onset was associated with higher rate of CBT, while adult onset was more prevalent in females.

Item Type: Article
Additional Information: Copyright 2016 Taylor and Francis. This is an Accepted Manuscript of an article published by Taylor & Francis in International Journal of Psychiatry in Clinical Practice on 19 July 2016, available online: http://dx.doi.org/10.1080/13651501.2016.1207087
Keywords: Age at onset, cognitive behavioural therapy, gender, obsessive–compulsive disorder, Age at onset, cognitive behavioural therapy, gender, obsessive-compulsive disorder, Age at onset, cognitive behavioural therapy, gender, obsessive–compulsive disorder, Psychiatry, 1103 Clinical Sciences, 1701 Psychology
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: International Journal of Psychiatry in Clinical Practice
ISSN: 1365-1501
Language: eng
Dates:
DateEvent
1 November 2016Published
19 July 2016Published Online
22 June 2016Accepted
PubMed ID: 27433835
Web of Science ID: WOS:000384532400002
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/108474
Publisher's version: https://doi.org/10.1080/13651501.2016.1207087

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