A novel erm(44) gene variant from a human Staphylococcus saprophyticus confers resistance to macrolides, lincosamides but not streptogramins.

More search options...

Strauss, C; Hu, Y; Coates, A; Perreten, V (2017) A novel erm(44) gene variant from a human Staphylococcus saprophyticus confers resistance to macrolides, lincosamides but not streptogramins. Antimicrobial Agents and Chemotherapy, 61 (1). e01655-16. ISSN 1098-6596 https://doi.org/10.1128/AAC.01655-16
SGUL Authors: Coates, Anthony Robert Milnes Hu, Yanmin

Preview

PDF Accepted Version
Available under License ["licenses_description_publisher" not defined].
Download (914kB) | Preview

Official URL: http://dx.doi.org/10.1128/AAC.01655-16

Abstract

A novel erm (44) gene variant, erm (44)v, has been identified by whole genome sequencing in a Staphylococcus saprophyticus isolated from the skin of a healthy person. It has the particularity to confer resistance to macrolides and lincosamides, but not to streptogramins B when expressed in S. aureus The erm (44)v gene resides on a 19,400-bp genomic island which contains phage-associated proteins and is integrated into the chromosome of S. saprophyticus.

Item Type:

Article

Additional Information:

Keywords:

Microbiology, 0605 Microbiology, 1108 Medical Microbiology, 1115 Pharmacology And Pharmaceutical Sciences

SGUL Research Institute / Research Centre:

Academic Structure > Infection and Immunity Research Institute (INII)

Journal or Publication Title:

Antimicrobial Agents and Chemotherapy

ISSN:

1098-6596

Language: