Mula, M
(2016)
Using anxiolytics in epilepsy: neurobiological, neuropharmacological and clinical aspects.
Epileptic Disorders, 18 (3).
pp. 217-227.
ISSN 1950-6945
https://doi.org/10.1684/epd.2016.0837
SGUL Authors: Mula, Marco
|
PDF
Accepted Version
Available under License ["licenses_description_publisher" not defined]. Download (400kB) | Preview |
|
|
Image (TIFF)
Accepted Version
Available under License ["licenses_description_publisher" not defined]. Download (47kB) | Preview |
|
|
Image (TIFF)
Accepted Version
Available under License ["licenses_description_publisher" not defined]. Download (127kB) | Preview |
Abstract
Anxiety disorders represent a common psychiatric comorbidity in patients with epilepsy, affecting prognosis and quality of life. However, they are still underdiagnosed and undertreated. In clinical practice, a number of compounds are currently used as anxiolytics, with benzodiazepines being the most popular. Other drug classes, especially antiepileptic drugs, are increasingly prescribed for the treatment of anxiety. This article discusses the neurobiological targets and basic neuropharmacological aspects of anxiolytics in order to give the reader clear insight into their activity and mechanism of action. Clinical data regarding the treatment of anxiety in both adults and children with epilepsy are also summarised, emphasising the need for further studies.
Item Type: | Article | ||||||
---|---|---|---|---|---|---|---|
Additional Information: | Copyright © 2016 John Libbey Eurotext. Téléchargé par un utilisateur anonyme le 16/09/2016. The final publication is available at link.springer.com | ||||||
Keywords: | GABA, antiepileptic drugs, anxiety, benzodiazepines, epilepsy, Neurology & Neurosurgery, 1103 Clinical Sciences | ||||||
SGUL Research Institute / Research Centre: | Academic Structure > Institute of Medical & Biomedical Education (IMBE) Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE ) |
||||||
Journal or Publication Title: | Epileptic Disorders | ||||||
ISSN: | 1950-6945 | ||||||
Language: | eng | ||||||
Dates: |
|
||||||
Publisher License: | Creative Commons: Attribution-Share Alike 3.0 IGO | ||||||
PubMed ID: | 27435111 | ||||||
Go to PubMed abstract | |||||||
URI: | https://openaccess.sgul.ac.uk/id/eprint/108230 | ||||||
Publisher's version: | https://doi.org/10.1684/epd.2016.0837 |
Statistics
Actions (login required)
![]() |
Edit Item |