Shah, T; Luck, S; Sharland, M; Kadambari, S; Heath, PT; Lyall, H
(2016)
Fifteen-minute consultation: diagnosis and management of congenital CMV.
Archives of Disease in Childhood Education and Practice Edition, 101 (5).
pp. 232-235.
ISSN 1743-0593
https://doi.org/10.1136/archdischild-2015-309656
SGUL Authors: Sharland, Michael Roy Luck, Suzanne Elizabeth
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Abstract
Congenital cytomegalovirus (cCMV) infection can result in permanent neurological problems and is a potentially preventable cause of sensorineural hearing loss in the UK. There is an urgency to diagnose and assess cCMV as antiviral treatment and has only been shown to be effective if started in the first 4 weeks of life. A recent randomised controlled trial of 6 months of treatment using oral valganciclovir has shown modest benefit in preventing hearing deterioration and in improving some neurodevelopmental outcomes. Parents and clinicians need to make a timely and informed choice regarding antiviral treatment and ensure that relevant non-pharmaceutical interventions are considered. This paper brings together the current evidence regarding the diagnosis and treatment of cCMV, consensus from two paediatric infectious diseases centres and outlines research priorities.
Item Type: | Article | ||||||||
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Additional Information: | Copyright Article author (or their employer) 2016. Produced by BMJ Publishing Group Ltd under licence. This article has been accepted for publication in Archives of Disease in Childhood Education and Practice Edition following peer review. The definitive copyedited, typeset version Fifteen-minute consultation: diagnosis and management of congenital CMV, Tejshri Shah, Suzanne Luck, Mike Sharland, Seilesh Kadambari, Paul Heath, Hermione Lyall, Arch Dis Child Educ Pract Ed edpract-2015-309656Published Online First: 15 June 2016 doi:10.1136/archdischild-2015-309656 is available online at: http://ep.bmj.com/content/early/2016/06/15/archdischild-2015-309656 | ||||||||
Keywords: | Infectious Diseases, Paediatric Practice, Virology, Infectious Diseases, Paediatric Practice, Virology, Pediatrics, 1114 Paediatrics And Reproductive Medicine | ||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Infection and Immunity Research Institute (INII) | ||||||||
Journal or Publication Title: | Archives of Disease in Childhood Education and Practice Edition | ||||||||
ISSN: | 1743-0593 | ||||||||
Language: | ENG | ||||||||
Dates: |
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Publisher License: | Publisher's own licence | ||||||||
PubMed ID: | 27307463 | ||||||||
Go to PubMed abstract | |||||||||
URI: | https://openaccess.sgul.ac.uk/id/eprint/108009 | ||||||||
Publisher's version: | https://doi.org/10.1136/archdischild-2015-309656 |
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