Brandt, C; Mula, M
(2016)
Anxiety disorders in people with epilepsy.
Epilepsy Behavior, 59.
pp. 87-91.
ISSN 1525-5069
https://doi.org/10.1016/j.yebeh.2016.03.020
SGUL Authors: Mula, Marco
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Abstract
Anxiety disorders are frequent, though probably underdiagnosed, comorbidities in epilepsy. Epilepsy and anxiety may share common neurobiological correlates as shown in animal models and suggested by studies demonstrating anxiety disorders before the manifestation of epilepsy. Comorbid anxiety disorders have a major impact on the affected patients' quality of life and may increase the risk for suicidality. Successful treatment of the epilepsy may alleviate anxiety symptoms. Treatment of anxiety is based on selective serotonin reuptake inhibitors, benzodiazepines (although only as second-line choices), and psychotherapy. Specific AEDs (especially pregabalin) have been shown to have anxiolytic properties. This paper is aimed at reviewing anxiety disorders in patients with epilepsy discussing current scientific evidence about pathophysiology, clinical aspects, and treatment strategies.
Item Type: | Article | ||||
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Additional Information: | © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | ||||
Keywords: | Comorbidity, Diagnosis, Prevalence, Quality of life, Treatment, Neurology & Neurosurgery, 1103 Clinical Sciences | ||||
SGUL Research Institute / Research Centre: | Academic Structure > Institute of Medical & Biomedical Education (IMBE) Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE ) |
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Journal or Publication Title: | Epilepsy Behavior | ||||
ISSN: | 1525-5069 | ||||
Language: | eng | ||||
Dates: |
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Publisher License: | Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0 | ||||
PubMed ID: | 27116536 | ||||
Go to PubMed abstract | |||||
URI: | https://openaccess.sgul.ac.uk/id/eprint/107953 | ||||
Publisher's version: | https://doi.org/10.1016/j.yebeh.2016.03.020 |
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