Parsons, TJ;
Sartini, C;
Ellins, EA;
Halcox, JP;
Smith, KE;
Ash, S;
Lennon, LT;
Wannamethee, SG;
Lee, IM;
Whincup, PH;
et al.
Parsons, TJ; Sartini, C; Ellins, EA; Halcox, JP; Smith, KE; Ash, S; Lennon, LT; Wannamethee, SG; Lee, IM; Whincup, PH; Jefferis, BJ
(2016)
Objectively measured physical activity and sedentary behaviour and ankle brachial index: Cross-sectional and longitudinal associations in older men.
Atherosclerosis, 247.
pp. 28-34.
ISSN 1879-1484
https://doi.org/10.1016/j.atherosclerosis.2016.01.038
SGUL Authors: Whincup, Peter Hynes
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Abstract
BACKGROUND: Associations between bouts of physical activity (PA), sedentary behaviour (SB) and cardiovascular disease, and their mutual independence are not well defined. A low ankle brachial index (ABI ≤0.9) indicates peripheral arterial disease (PAD) and is predictive of cardiovascular events and functional impairment. We investigated the independence of PA and SB and the importance of bout duration in relation to ABI using objective measures. METHODS: 945 men from the British Regional Heart Study, mean age 78.4 y, had concurrent measurements of ABI (Vicorder) and physical activity (Actigraph GT3X accelerometer); 427 men also had accelerometer measurements one year previously and contributed data to longitudinal analyses. RESULTS AND CONCLUSION: In cross-sectional analyses, after adjusting for covariates each extra 10 min of moderate and vigorous PA per day was associated with an OR of 0.81 (95% CI 0.72, 0.91) for a low ABI, a stronger association than for light PA (OR 0.85, 95% CI 0.75, 0.98). Each extra 30 min of SB was associated with an OR of 1.19 (95% CI 1.07, 1.33) for a low ABI. Associations between moderate and vigorous PA and ABI persisted after adjustment for light PA or SB. Bout lengths for PA and SB were not associated with a low ABI. One year changes in PA or SB were not associated with low ABI. All physical activity and lower levels of SB, regardless of bout duration were inversely associated with ABI; more intense PA showed a stronger association. No associations between changes in PA and ABI were observed, but power may have been limited.
Item Type: | Article | |||||||||||||||
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Additional Information: | © 2016 The Authors. Published by Elsevier Ireland Ltd. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/). | |||||||||||||||
Keywords: | Accelerometer, Ankle brachial index, Epidemiology, Men, Peripheral arterial disease, Physical activity, Cardiovascular System & Hematology, 1103 Clinical Sciences, 1102 Cardiovascular Medicine And Haematology | |||||||||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Population Health Research Institute (INPH) | |||||||||||||||
Journal or Publication Title: | Atherosclerosis | |||||||||||||||
ISSN: | 1879-1484 | |||||||||||||||
Language: | eng | |||||||||||||||
Publisher License: | Creative Commons: Attribution 4.0 | |||||||||||||||
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PubMed ID: | 26854973 | |||||||||||||||
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URI: | https://openaccess.sgul.ac.uk/id/eprint/107837 | |||||||||||||||
Publisher's version: | https://doi.org/10.1016/j.atherosclerosis.2016.01.038 |
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