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Insertion of Epicatechin Gallate into the Cytoplasmic Membrane of Methicillin-resistant Staphylococcus aureus Disrupts Penicillin-binding Protein (PBP) 2a-mediated beta-Lactam Resistance by Delocalizing PBP2

Bernal, P; Lemaire, S; Pinho, MG; Mobashery, S; Hinds, J; Taylor, PW (2010) Insertion of Epicatechin Gallate into the Cytoplasmic Membrane of Methicillin-resistant Staphylococcus aureus Disrupts Penicillin-binding Protein (PBP) 2a-mediated beta-Lactam Resistance by Delocalizing PBP2. JOURNAL OF BIOLOGICAL CHEMISTRY, 285 (31). 24055 - 24065 (11). ISSN 0021-9258 https://doi.org/10.1074/jbc.M110.114793
SGUL Authors: Hinds, Jason

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Item Type: Article
Additional Information: PubMed ID: 20516078
Keywords: Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, MODIFIER (-)-EPICATECHIN GALLATE, GRAM-POSITIVE BACTERIA, WALL-STRESS STIMULON, CELL-WALL, LIPID-BILAYERS, TEA CATECHINS, GREEN TEA, EPIGALLOCATECHIN GALLATE, PHOSPHOLIPID-COMPOSITION, IN-VITRO, Anisotropy, Anti-Bacterial Agents, Catechin, Cell Wall, Cytoplasm, Drug Resistance, Bacterial, Gene Expression Regulation, Bacterial, Lysine, Methicillin, Methicillin-Resistant Staphylococcus aureus, Microscopy, Fluorescence, Oligonucleotide Array Sequence Analysis, Penicillin-Binding Proteins, Phosphatidylglycerols, beta-Lactams
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: JOURNAL OF BIOLOGICAL CHEMISTRY
ISSN: 0021-9258
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Dates:
DateEvent
30 July 2010Published
Web of Science ID: WOS:000280291400056
Download EPMC Full text (HTML)
URI: https://openaccess.sgul.ac.uk/id/eprint/465
Publisher's version: https://doi.org/10.1074/jbc.M110.114793

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