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Post-mortem perinatal imaging: what is the evidence?

Shelmerdine, SC; Arthurs, OJ (2023) Post-mortem perinatal imaging: what is the evidence? Br J Radiol, 96 (1147). p. 20211078. ISSN 1748-880X https://doi.org/10.1259/bjr.20211078
SGUL Authors: Shelmerdine, Susan Cheng

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Abstract

Post-mortem imaging for the investigation of perinatal deaths is an acceptable tool amongst parents and religious groups, enabling a less invasive autopsy examination. Nevertheless, availability is scarce nationwide, and there is some debate amongst radiologists regarding the best practice and optimal protocols for performing such studies. Much of the published literature to date focusses on single centre experiences or interesting case reports. Diagnostic accuracy studies are available for a variety of individual imaging modalities (e.g. post-mortem CT, MRI, ultrasound and micro-CT), however, assimilating this information is important when attempting to start a local service.In this article, we present a comprehensive review summarising the latest research, recently published international guidelines, and describe which imaging modalities are best suited for specific indications. When the antenatal clinical findings are not supported by the post-mortem imaging, we also suggest how and when an invasive autopsy may be considered. In general, a collaborative working relationship within a multidisciplinary team (consisting of radiologists, radiographers, the local pathology department, mortuary staff, foetal medicine specialists, obstetricians and bereavement midwives) is vital for a successful service.

Item Type: Article
Additional Information: © 2022 The Authors. Published by the British Institute of Radiology under the terms of the Creative Commons Attribution 4.0 Unported License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Keywords: Humans, Pregnancy, Female, Autopsy, Magnetic Resonance Imaging, Perinatal Death, Ultrasonography, Radiologists, Humans, Magnetic Resonance Imaging, Ultrasonography, Autopsy, Pregnancy, Female, Perinatal Death, Radiologists, 1103 Clinical Sciences, Nuclear Medicine & Medical Imaging
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: Br J Radiol
ISSN: 1748-880X
Language: eng
Dates:
DateEvent
July 2023Published
25 April 2022Published Online
4 April 2022Accepted
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
MR/R002118/1Medical Research Councilhttp://dx.doi.org/10.13039/501100000265
NIHR301322National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
NIHR-CDF-2017-10-037National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
PubMed ID: 35451852
Web of Science ID: WOS:001027904200004
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/115662
Publisher's version: https://doi.org/10.1259/bjr.20211078

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