Issak, S; Kanaan, R; Nielsen, G; Fini, NA; Williams, G
(2023)
Functional Gait Disorders: Clinical presentations, Phenotypes and Implications for treatment.
Brain Inj, 37 (5).
pp. 437-445.
ISSN 1362-301X
https://doi.org/10.1080/02699052.2023.2165158
SGUL Authors: Nielsen, Glenn
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Abstract
BACKGROUND: Functional Gait Disorders (FGD) are a common presentation of motor-Functional Neurological Disorders (motor-FND) that affect walking ability. AIM: To provide a narrative review of the current literature on FGD. METHODS: A narrative overview of published literature was undertaken, based on a systematic search of relevant databases, authoritative texts and citation tracking. RESULTS: FGD is multidimensional and disabling, with numerous phenotypes described in the literature, including 'knee buckling,' 'astasia-abasia' and 'excessive slowness.' Motor symptoms such as weakness or tremor, and non-motor symptoms, such as pain and fatigue may contribute to the disability and distress in FGD. Phenotypic features and clinical signs are seen in FGD that demonstrate inconsistency and incongruity with structural disease. A limited number of treatment studies have specifically focussed on FGD, however, reporting of outcomes from motor-FND cohorts has demonstrated short and long-term improvements in walking ability through multidisciplinary rehabilitation. CONCLUSIONS: The relative contribution of motor and non-motor symptoms in FGD remains unknown, but it is likely that non-motor symptoms increase the illness burden and should be considered during assessment and treatment. Recommended treatment for FGD involves multidisciplinary rehabilitation, but optimum treatment elements are yet to be determined.
Item Type: | Article | ||||||||
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Additional Information: | © 2023 The Author(s). Published with license by Taylor & Francis Group, LLC. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. | ||||||||
Keywords: | clinical presentations, functional gait disorders, functional neurological disorders, phenotypes, treatment, Humans, Gait, Walking, Movement Disorders, Conversion Disorder, Fatigue, Humans, Movement Disorders, Fatigue, Gait, Walking, Conversion Disorder, functional neurological disorders, functional gait disorders, clinical presentations, phenotypes, treatment, 11 Medical and Health Sciences, 17 Psychology and Cognitive Sciences, Rehabilitation | ||||||||
SGUL Research Institute / Research Centre: | Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) | ||||||||
Journal or Publication Title: | Brain Inj | ||||||||
ISSN: | 1362-301X | ||||||||
Language: | eng | ||||||||
Dates: |
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Publisher License: | Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0 | ||||||||
PubMed ID: | 36617694 | ||||||||
Web of Science ID: | WOS:000909556400001 | ||||||||
Go to PubMed abstract | |||||||||
URI: | https://openaccess.sgul.ac.uk/id/eprint/115622 | ||||||||
Publisher's version: | https://doi.org/10.1080/02699052.2023.2165158 |
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