Nooredinvand, HA; Poullis, A
(2022)
Emerging role of colorectal mucus in gastroenterology diagnostics.
World J Gastroenterol, 28 (12).
pp. 1220-1225.
ISSN 2219-2840
https://doi.org/10.3748/wjg.v28.i12.1220
SGUL Authors: Poullis, Andrew
Abstract
Colonoscopy is currently the gold standard for diagnosis of inflammatory bowel disease (IBD) and colorectal cancer (CRC). This has the obvious drawback of being invasive as well as carrying a small risk. The most widely used non-invasive approaches include the use of faecal calprotectin in the case of IBD and fecal immunochemical test in the case of CRC. However, the necessity of stool collection limits their acceptability for some patients. Over the recent years, there has been emerging data looking at the role of non-invasively obtained colorectal mucus as a screening and diagnostic tool in IBD and CRC. It has been shown that the mucus rich material obtained by self-sampling of anal surface following defecation, can be used to measure various biomarkers that can aid in diagnosis of these conditions.
| Item Type: |
Article
|
| Additional Information: |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Nooredinvand HA, Poullis A. Emerging role of colorectal mucus in gastroenterology diagnostics. World J Gastroenterol 2022; 28(12): 1220-1225 [PMID: 35431508 DOI: 10.3748/wjg.v28.i12.1220] |
| Keywords: |
Colorectal cancer, Colorectal mucus, Crohn's disease, Faecal calprotectin, Inflammatory bowel disease, Ulcerative colitis, Biomarkers, Colonoscopy, Colorectal Neoplasms, Feces, Gastroenterology, Humans, Inflammatory Bowel Diseases, Leukocyte L1 Antigen Complex, Mucus, Sensitivity and Specificity, Colorectal mucus, Inflammatory bowel disease, Crohn's disease, Ulcerative colitis, Colorectal cancer, Faecal calprotectin, 1103 Clinical Sciences, Gastroenterology & Hepatology |
| SGUL Research Institute / Research Centre: |
Academic Structure > Institute of Medical & Biomedical Education (IMBE) |
| Journal or Publication Title: |
World J Gastroenterol |
| ISSN: |
2219-2840 |
| Language: |
eng |
| Dates: |
| Date | Event |
|---|
| 28 March 2022 | Published | | 23 February 2022 | Accepted |
|
| Publisher License: |
Creative Commons: Attribution-Noncommercial 4.0 |
| PubMed ID: |
35431508 |
| Web of Science ID: |
WOS:000814024700003 |
 |
Go to PubMed abstract |
| URI: |
https://openaccess.sgul.ac.uk/id/eprint/115132 |
| Publisher's version: |
https://doi.org/10.3748/wjg.v28.i12.1220 |
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