SORA

Advancing, promoting and sharing knowledge of health through excellence in teaching, clinical practice and research into the prevention and treatment of illness

The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: Findings from the Global Burden of Disease Study 2019.

Castelpietra, G; Knudsen, AKS; Agardh, EE; Armocida, B; Beghi, M; Iburg, KM; Logroscino, G; Ma, R; Starace, F; Steel, N; et al. Castelpietra, G; Knudsen, AKS; Agardh, EE; Armocida, B; Beghi, M; Iburg, KM; Logroscino, G; Ma, R; Starace, F; Steel, N; Addolorato, G; Andrei, CL; Andrei, T; Ayuso-Mateos, JL; Banach, M; Bärnighausen, TW; Barone-Adesi, F; Bhagavathula, AS; Carvalho, F; Carvalho, M; Chandan, JS; Chattu, VK; Couto, RAS; Cruz-Martins, N; Dargan, PI; Deuba, K; da Silva, DD; Fagbamigbe, AF; Fernandes, E; Ferrara, P; Fischer, F; Gaal, PA; Gialluisi, A; Haagsma, JA; Haro, JM; Hasan, MT; Hasan, SS; Hostiuc, S; Iacoviello, L; Iavicoli, I; Jamshidi, E; Jonas, JB; Joo, T; Jozwiak, JJ; Katikireddi, SV; Kauppila, JH; Khan, MAB; Kisa, A; Kisa, S; Kivimäki, M; Koly, KN; Koyanagi, A; Kumar, M; Lallukka, T; Langguth, B; Ledda, C; Lee, PH; Lega, I; Linehan, C; Loureiro, JA; Madureira-Carvalho, ÁM; Martinez-Raga, J; Mathur, MR; McGrath, JJ; Mechili, EA; Mentis, A-FA; Mestrovic, T; Miazgowski, B; Mirica, A; Mirijello, A; Moazen, B; Mohammed, S; Mulita, F; Nagel, G; Negoi, I; Negoi, RI; Nwatah, VE; Padron-Monedero, A; Panda-Jonas, S; Pardhan, S; Pasovic, M; Patel, J; Petcu, I-R; Pinheiro, M; Pollok, RCG; Postma, MJ; Rawaf, DL; Rawaf, S; Romero-Rodríguez, E; Ronfani, L; Sagoe, D; Sanmarchi, F; Schaub, MP; Sharew, NT; Shiri, R; Shokraneh, F; Sigfusdottir, ID; Silva, JP; Silva, R; Socea, B; Szócska, M; Tabarés-Seisdedos, R; Torrado, M; Tovani-Palone, MR; Vasankari, TJ; Veroux, M; Viner, RM; Werdecker, A; Winkler, AS; Hay, SI; Ferrari, AJ; Naghavi, M; Allebeck, P; Monasta, L (2022) The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: Findings from the Global Burden of Disease Study 2019. Lancet Reg Health Eur, 16. p. 100341. ISSN 2666-7762 https://doi.org/10.1016/j.lanepe.2022.100341
SGUL Authors: Pollok, Richard Charles G

[img]
Preview
PDF Published Version
Available under License Creative Commons Attribution.

Download (1MB) | Preview
[img] Microsoft Word (.docx) (Supplementary materials 1) Published Version
Available under License Creative Commons Attribution.

Download (495kB)
[img] Microsoft Word (.docx) (Supplementary materials 2) Published Version
Available under License Creative Commons Attribution.

Download (1MB)
[img] Microsoft Word (.docx) (Supplementary materials 3) Published Version
Available under License Creative Commons Attribution.

Download (92kB)

Abstract

Background: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading causes of disease burden over time. Methods: Prevalence, incidence, Years Lived with Disability (YLDs) and Years of Life Lost (YLLs) from mental disorders (MDs), substance use disorders (SUDs) and self-harm were estimated for young people aged 10-24 years in 31 European countries. Rates per 100,000 population, percentage changes in 1990-2019, 95% Uncertainty Intervals (UIs), and correlations with Sociodemographic Index (SDI), were estimated. Findings: In 2019, rates per 100,000 population were 16,983 (95% UI 12,823 - 21,630) for MDs, 3,891 (3,020 - 4,905) for SUDs, and 89·1 (63·8 - 123·1) for self-harm. In terms of disability, anxiety contributed to 647·3 (432-912·3) YLDs, while in terms of premature death, self-harm contributed to 319·6 (248·9-412·8) YLLs, per 100,000 population. Over the 30 years studied, YLDs increased in eating disorders (14·9%;9·4-20·1) and drug use disorders (16·9%;8·9-26·3), and decreased in idiopathic developmental intellectual disability (-29·1%;23·8-38·5). YLLs decreased in self-harm (-27·9%;38·3-18·7). Variations were found by sex, age-group and country. The burden of SUDs and self-harm was higher in countries with lower SDI, MDs were associated with SUDs. Interpretation: Mental health conditions represent an important burden among young people living in Europe. National policies should strengthen mental health, with a specific focus on young people. Funding: The Bill and Melinda Gates Foundation.

Item Type: Article
Additional Information: Copyright © 2022 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
Keywords: Europe, Mental disorders, Mental health, Self-harm, Substance use, Young people, Young people, Mental health, Mental disorders, Self-harm, Substance use, Europe
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Lancet Reg Health Eur
ISSN: 2666-7762
Language: eng
Dates:
DateEvent
May 2022Published
1 April 2022Published Online
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
UIDP/04378/2020Research Unit on Applied Molecular Biosciences - UCIBIOUNSPECIFIED
LA/P/0140/2020Associate Laboratory Institute for Health and Bioeconomy - i4HBUNSPECIFIED
UIDB/50006/2020Ministério da Ciência, Tecnologia e Ensino Superiorhttp://dx.doi.org/10.13039/501100006111
APP1121516National Health and Medical Research Councilhttp://dx.doi.org/10.13039/501100000925
SCAF/15/02NHS Research ScotlandUNSPECIFIED
MC_UU_00022/2Medical Research Councilhttp://dx.doi.org/10.13039/501100000265
SPHSU17Scottish Government Chief Scientist OfficeUNSPECIFIED
221854/Z/20/ZWellcome Trusthttp://dx.doi.org/10.13039/100004440
MR/R024227/1Medical Research Councilhttp://dx.doi.org/10.13039/501100000265
MR/S011676/1Medical Research Councilhttp://dx.doi.org/10.13039/501100000265
K43 TW010716-04National Institutes of Healthhttp://dx.doi.org/10.13039/100000002
29/26/2020Social Insurance Institute of FinlandUNSPECIFIED
CEECINST/00049/2018Fundação para a Ciência e a TecnologiaUNSPECIFIED
T2EDK-02222Operational Program Competitiveness, Entrepreneurship and InnovationUNSPECIFIED
UIDP/04378/2021FCT/MCTESUNSPECIFIED
LA/P/0140/2021FCT/MCTESUNSPECIFIED
PubMed ID: 35392452
Web of Science ID: WOS:000797600600006
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/114785
Publisher's version: https://doi.org/10.1016/j.lanepe.2022.100341

Actions (login required)

Edit Item Edit Item